Results 81 to 90 of about 1,150,719 (355)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Propfan noise propagation [PDF]
The unconventional supersonic tip speed of advanced propellers has led to uncertainties about Propfan's noise acceptability and compliance with Federal Aviation Noise Regulation (FAR 36).
George, Albert R., Sim, Ben WEL-C.
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Competition in the German Broadband Access Market [PDF]
This paper gives a survey of the current state of competition in the German Broadband access market. Existing regulations and their impact on the deployment of high-speed Internet access are evaluated.
Vanberg, Margit A.
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Full-order adaptive sliding mode control with extended state observer for high-speed PMSM speed regulation. [PDF]
Sci Rep, 2023 Luo M +6 more
europepmc +1 more source
Performance of the electrical controls for the Mini-Brayton system [PDF]
The design theory and performance of a breadboard of the proposed Mini-Brayton electrical control system is presented. The Mini-Brayton is a nuclear isotope powered dynamic power conversion system. Testing was performed with an electronic simulation of a
Birchenough, A. G.
core +1 more source
Application of fuzzy logic to power system stabilizer [PDF]
, 2008 Power systems stability is a complex problem which was first recognised in 1920 and has been widely investigated by power system engineers ever since.
Abdullah, Shahrum Shah
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Effective Labor Regulation and Microeconomic Flexibility [PDF]
Microeconomic flexibility, by facilitating the process of creative-destruction, is at the core of economic growth in modern market economies. The main reason for why this process is not infinitely fast is the presence of adjustment costs, some of them ...
Alejandro Micco +2 more
core +3 more sources