Results 91 to 100 of about 1,157,151 (303)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Competing on Speed [PDF]

open access: yes
Two forces have reshaped global securities markets in the last decade: Exchanges operate at much faster speeds and the trading landscape has become more fragmented. In order to analyze the positive and normative implications of these evolutions, we study
Emiliano Pagnotta, Thomas Philippon
core  

Reversible Speed Regulation of Self-Propelled Janus Micromotors via Thermoresponsive Bottle-Brush Polymers. [PDF]

open access: yesChemistry, 2021
Fiedler C   +8 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Effective Labor Regulation and Microeconomic Flexibility [PDF]

open access: yes
Microeconomic flexibility, by facilitating the process of creative-destruction, is at the core of economic growth in modern market economies. The main reason for why this process is not infinitely fast is the presence of adjustment costs, some of them ...
Alejandro Micco   +2 more
core   +3 more sources

Research on rotor-side frequency conversion speed regulation technology for high voltage wound-rotor motor

open access: yesGong-kuang zidonghua, 2018
In view of problems of technical difficulties, high cost and high voltage requirements for power electronic components in current high voltage wound-rotor motor using stator-side high voltage inverter for frequency conversion speed regulation, a rotor ...
CHENG Guodong   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Valve-Pump Parallel Variable Mode Control for Complex Speed Regulation Processes

open access: yesComplexity, 2018
To improve comprehensive performances of hydraulic systems with complex speed regulation processes, this paper proposes a new control scheme, valve-pump parallel variable mode control, which can change control modes according to control requirements and ...
Haigang Ding   +3 more
doaj   +1 more source

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