FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Speed Choice, Speed Preference and Risk Perception: Relevance for the Problem of Speed Variability in Traffic [PDF]
, 2014 Fifty percent of drives have been found to frequently violate speed limits (OECD/ECMT, 2006), and speed limit compliance appears to depend on the perceived credibility of a road’s speed limit (Goldenbeld & van Schagen, 2007). Credibility of speed limits,
Ahie, Liv Marit
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Comparative study on PID for DC motor speed regulation [PDF]
MATEC Web of ConferencesBecause of its straightforward design and excellent adjustment efficiency, PID (proportional-integral-derivative) controllers are frequently employed in motor speed control.
Han Xiangda
doaj +1 more source
Full-order adaptive sliding mode control with extended state observer for high-speed PMSM speed regulation. [PDF]
Sci Rep, 2023 Luo M +6 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Research on hydraulic system with three-stage speed regulation of mine-used cable winding device
Gong-kuang zidonghua, 2019 In view of the problem that cable winding speed cannot be synchronized with speed of continuous shearer, based on analysis of principle of hydraulic system with three-stage speed regulation of the cable winding device, simulation model of hydraulic ...
LI Pengpeng +4 more
doaj +1 more source
Reversible Speed Regulation of Self-Propelled Janus Micromotors via Thermoresponsive Bottle-Brush Polymers. [PDF]
Chemistry, 2021 Fiedler C +8 more
europepmc +1 more source
Speed-Control of Energy Regulation Based Variable-Speed Electrohydraulic Drive
Strojniški vestnik – Journal of Mechanical Engineering, 2013 The variable-speed electrohydraulic drive is a promising drive principle due to its high energy efficiency and large speed-range. However, its slow response and poor low-speed behaviour limit its application. To address these disadvantages, a energy regulation based variable-speed electrohydraulic drive is proposed.
Chen, Guojin +3 more
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source