Results 111 to 120 of about 290,778 (266)

Conflict resolution by speed regulation

open access: yes, 2012
To overcome the traffic growth predicted by current ATM research programs in Europe and the US, we propose a new model to avoid conflicts based on small speed regulations, as depicted in the ERASMUS project [6], with interval conflict constraints as in [2].
Galloux, Maxime   +3 more
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

RESEARCH ON FUZZY CONTROL SIMULATION OF CVT RATIO BASED ON ENGINE SPEED REGULATION CHARACTERISTICS

open access: yesJixie qiangdu, 2019
According to the load characteristics and speed regulation characteristics of the engine,the steady-state torque model is established and the optimum power and economy curves of engine are determined. Then the engine target speed is obtained by using the
GUO Wei, JIA GaoXiang, ZHANG Wu, CHEN Ya
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Research on Traction Speed Regulation and Braking Device of Pipeline Intelligent Plugging Robot

open access: yes工程科学与技术
ObjectiveWith increasing pipeline mileage and service time, more pipelines are being damaged due to environmental corrosion and human factors. This damage results in interruptions in transport and leakage of oil and gas, which in turn causes economic ...
TANG Yang   +3 more
doaj  

Research of Full Range Speed-regulation System Based on Bivariate 6-pulse Wave AC-AC Converter

open access: yesGong-kuang zidonghua, 2010
The paper proposed a design scheme of full range speed-regulation system based on bivariate 6-pulse wave AC-AC converter. It analyzed control principle of bivariate 6-pulse wave AC-AC converter, introduced characteristics and design of main circuit and ...
JIA Ji-guang, DU Shao-tong
doaj  

On regulation of engine speed.

open access: yesOn regulation of engine speed.
種別 ...
openaire  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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