Results 81 to 90 of about 1,157,151 (303)
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Research on hydraulic system with three-stage speed regulation of mine-used cable winding device
In view of the problem that cable winding speed cannot be synchronized with speed of continuous shearer, based on analysis of principle of hydraulic system with three-stage speed regulation of the cable winding device, simulation model of hydraulic ...
LI Pengpeng +4 more
doaj +1 more source
Competition in the German Broadband Access Market [PDF]
This paper gives a survey of the current state of competition in the German Broadband access market. Existing regulations and their impact on the deployment of high-speed Internet access are evaluated.
Vanberg, Margit A.
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Speed-Control of Energy Regulation Based Variable-Speed Electrohydraulic Drive
The variable-speed electrohydraulic drive is a promising drive principle due to its high energy efficiency and large speed-range. However, its slow response and poor low-speed behaviour limit its application. To address these disadvantages, a energy regulation based variable-speed electrohydraulic drive is proposed.
Chen, Guojin +3 more
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Airbus windshear warning and guidance system [PDF]
From its first designed airplane, Airbus considered mandatory a help in the crew's decision-making process to initiate an escape maneuver and help to successfully realize it.
Bonafe, J. L.
core +1 more source
Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis
Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''.
Furusawa, Chikara, Kaneko, Kunihiko
core +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Full-order adaptive sliding mode control with extended state observer for high-speed PMSM speed regulation. [PDF]
Luo M +6 more
europepmc +1 more source

