Results 121 to 130 of about 2,712 (266)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

In-air and in-water performance comparison of Passive Gamma Emission Tomography with activated Co-60 rods. [PDF]

Sci Rep, 2023
Virta R, Bubba TA, Moring M, Siltanen S, Honkamaa T, Dendooven P.   +5 more
europepmc   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source

Reactivity Risk in PWR Spent Fuel Pools

Reactivity Risk in PWR Spent Fuel Pools
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Perceived Suitability for Being a Dental Hygienist and Self‐Compassion: A 6‐Month Longitudinal Cohort Study

Journal of Dental Education, EarlyView.
ABSTRACT Objectives Perceived professional suitability—students' judgment of whether they are well‐suited to their profession—may shift within a semester, yet longitudinal evidence in dental hygiene education is limited. We examined 6‐month changes in perceived suitability and their psychological associations.
Maya Izumi, Hsiu‐Yueh Liu, Sumio Akifusa   +2 more
wiley   +1 more source

I-129 in Nuclear Waste: Much Ado About Nothing. [PDF]

Dose Response
Henry H, Welsh JS.
europepmc   +1 more source

Preparing for Tomorrow's Teamwork: Insights From eSports on How Human Expertise Shapes Training Needs for AI‐Integrated Work

Journal of Organizational Behavior, EarlyView.
ABSTRACT As organizations increasingly adopt human‐AI teams (HATs), understanding how to enhance team performance is paramount. A crucially underexplored area for supporting HATs is training, particularly helping human teammates to work with these inorganic counterparts.
Caitlin M. Lancaster, Christopher Flathmann, Jennifer Hsu, Nathan J. McNeese, Thomas A. O'Neill, Eduardo Salas   +5 more
wiley   +1 more source

Physics-based forward model for near-real-time quantitative imaging of spent nuclear fuel assemblies. [PDF]

Sci Rep
Fang M, Virta R, Dendooven P, Altmann Y, Di Fulvio A.   +4 more
europepmc   +1 more source