Results 191 to 200 of about 1,124,248 (284)

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington   +4 more
wiley   +1 more source

TMEM16A Ca2+‐activated Cl− channel: Functional interactions with cytoskeletal and membrane‐associated proteins

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura   +4 more
wiley   +1 more source

The rapidly evolving X-linked MIR-506 family fine-tunes spermatogenesis to enhance sperm competition. [PDF]

open access: yesElife
Wang Z   +17 more
europepmc   +1 more source

Fifty years of sperm competition: the structure of a scientific revolution. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci, 2020
Simmons LW, Wedell N.
europepmc   +1 more source

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell   +3 more
wiley   +1 more source

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi   +12 more
wiley   +1 more source

Protective Effects of Lactobacillus‐Derived Probiotics and Postbiotics on Renal and Reproductive Function in Escherichia coli–Infected Rats

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A Lactobacillus‐derived probiotic and postbiotic mixture alleviates E. coli–induced renal and reproductive dysfunction by modulating oxidative stress, inflammatory responses, and apoptosis, leading to improved tissue integrity and sperm quality. ABSTRACT Background Escherichia coli infections of the genitourinary tract are a major cause of renal and ...
Saeid Sedghi   +2 more
wiley   +1 more source

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