Results 61 to 70 of about 1,104,726 (307)

Cannibalism and protective behavior of eggs in Arctic charr (Salvelinus alpinus)

open access: yesEcology and Evolution, 2021
From video recordings of spawning events, we quantified protective and cannibalistic behavior of Arctic charr occurring immediately after spawning. The number of fish cannibalizing on stray eggs was examined regarding (a) whether more than one male shed ...
Marilena Frye   +3 more
doaj   +1 more source

Egg chemoattractants moderate intraspecific sperm competition

open access: yesEvolution Letters, 2017
Interactions among eggs and sperm are often assumed to generate intraspecific variation in reproductive fitness, but the specific gamete‐level mechanisms underlying competitive fertilization success remain elusive in most species.
Rowan A. Lymbery   +2 more
semanticscholar   +1 more source

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

open access: yesAdvanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu   +10 more
wiley   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

open access: yesAdvanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun   +9 more
wiley   +1 more source

Faster and more efficient swimming: energy consumption of murine spermatozoa under sperm competition†

open access: yesBiology of Reproduction, 2018
ATP supply is essential for sperm performance and increases in ATP content coevolve with enhanced sperm swimming velocity as a response to sperm competition in rodents.
Maximiliano Tourmente   +2 more
semanticscholar   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

open access: yesAdvanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang   +12 more
wiley   +1 more source

Consistent paternity skew through ontogeny in Peron's tree frog (Litoria peronii). [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:A large number of studies in postcopulatory sexual selection use paternity success as a proxy for fertilization success. However, selective mortality during embryonic development can lead to skews in paternity in situations of polyandry and ...
Craig D H Sherman   +2 more
doaj   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang   +2 more
wiley   +1 more source

Loss‐Based Ensemble Generative Adversarial Network Model for Enhancing the Sperm Morphology Classification

open access: yesAdvanced Intelligent Systems, EarlyView.
A loss‐based ensemble generative adversarial network (GAN) framework is proposed to address mode collapse in sperm morphology classification. By integrating spatial augmentation and multiple GAN models, the study enhances synthetic data quality. The Shifted Window Transformer achieves 95.37% accuracy on the HuSHeM dataset, outperforming previous ...
Berke Cansiz   +2 more
wiley   +1 more source

Rogue sperm indicate sexually antagonistic coevolution in nematodes. [PDF]

open access: yesPLoS Biology, 2014
Intense reproductive competition often continues long after animals finish mating. In many species, sperm from one male compete with those from others to find and fertilize oocytes.
Ronald E Ellis, Lukas Schärer
doaj   +1 more source

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