Reproductive functions and fertility preservation in men with sickle cell disease
Abstract Background Sickle cell disease (SCD) is a prevalent hereditary disorder with significant morbidity, including potential impacts on male fertility. This study aims to evaluate the semen parameters in men with SCD and assess the outcomes of fertility preservation strategies.
Clarisse Leblanc+12 more
wiley +1 more source
Abstract Background Hypogonadism and infertility are two conditions that are heavily affected by overweight and obesity in the male patient. Glucagon‐like peptide 1 agonists (GLP‐1RAs) are a recently introduced class of antidiabetic drugs with powerful weight‐loss effect; this may induce an indirect positive effect on the testicular function ...
Gianmaria Salvio+6 more
wiley +1 more source
Exploring the link between periodontal disease and sperm quality: a comprehensive systematic review study. [PDF]
Mortazavi V+3 more
europepmc +1 more source
Abstract Background Classic Klinefelter syndrome (KS) is characterized by one extra X chromosome (47, XXY), leading to hypergonadotropic hypogonadism and higher risk of alterations in glycolipid homeostasis, cardiovascular diseases, and low bone mineral density. Most frequently, KS is diagnosed in adulthood because of infertility.
Giordana Ferraioli+7 more
wiley +1 more source
Sweet Drinks, Sour Consequences: The Impact of Sugar-Sweetened Beverages on Sperm Health, a Narrative Review. [PDF]
Win WKY, Wong MW, Benny P, Huang Z.
europepmc +1 more source
Normozoospermic men in infertile couples: Potential benefit of early medical diagnostic procedures
Abstract Introduction Infertility, defined as the inability to achieve pregnancy despite regular, unprotected sexual intercourse for 1 year, affects approximately 15% of couples. Male factors contribute to 50% of these cases. The necessity of andrological evaluations for male partners of infertile couples with normozoospermia is currently under ...
Simone Bier+3 more
wiley +1 more source
LIN 28B expression is downregulated in mature spermatozoa of oligozoospermic men and associates with genetic variants previously linked to pubertal onset. [PDF]
Lardone MC+8 more
europepmc +1 more source
Abstract Background Fetal exposure to endocrine‐disrupting chemicals (EDCs) has been associated with reduced male fecundity, but with few studies considering chemical mixtures. Objectives We assessed the association between fetal exposure to a mixture of EDCs and biomarkers of male fecundity in young adulthood.
Sidsel Dan Hull+11 more
wiley +1 more source
Applications of spatial transcriptomics in studying spermatogenesis
Abstract Spermatogenesis is a complex differentiation process that is facilitated by a series of cellular and molecular events. High‐throughput genomics approaches, such as single‐cell RNA sequencing, have begun to enable the systematic characterization of these events. However, the loss of tissue context because of tissue disassociations in the single‐
Qianlan Xu, Haiqi Chen
wiley +1 more source
Reduction of Torsion-Detorsion-Induced Testicular Damage With Hawthorn Extract: Oxidative, Hormonal, and Histological Effects. [PDF]
Bozok ÜG, Özcan GB, Cinar FU.
europepmc +1 more source