Results 61 to 70 of about 47,453 (299)

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

open access: yesAdvanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li   +5 more
wiley   +1 more source

IGF2 and IGF1R mRNAs Are Detectable in Human Spermatozoa

open access: yesThe World Journal of Men's Health, 2020
Purpose: Oligozoospermia is highly prevalent worldwide. Studies have reported a lower methylation rate in the H19 differentially methylated region at the sperm level in oligozoospermic patients than in controls.
Rossella Cannarella   +6 more
doaj   +1 more source

Sperm Count Improvement in a Cancer-Surviving Patient [PDF]

open access: yes, 2015
Objective: To describe the case of a cancer-surviving patient who was treated with an aromatase inhibitor for fertility reasons with successful results.
Margarida M. Vieira   +2 more
core   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

SPERMATOGENESIS INDICES IN INBRED STRAINS DD/HE AND BALB/CLAC AND THEIR F1 RECIPROCAL CROSSES

open access: yesВавиловский журнал генетики и селекции, 2014
We have shown that among 13 inbred mice strains males the DD/He strain has the lowest proportion of mobile sperm and moderate sperm count and proportion of abnormal sperm heads.
M. A. Kleshchev   +2 more
doaj  

The Effect of Mangosteen Peel Extract on Sperm Motility and Sperm Count of Swiss Webster Mice Induced by Hard Physical Exercise [PDF]

open access: yes, 2015
High-intensity physical exercises can increase oxidative stress, causing damage to reproductive system. The purpose of this study was to determine the effect of mangosteen peel extract on sperm motility and  sperm count of  Swiss Webster mice induced by ...
Ardi Prawira   +2 more
core   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

open access: yesAdvanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie   +20 more
wiley   +1 more source

Urinary isoflavone concentrations and semen parameters of Japanese men seeking fertility treatment

open access: yesAsian Journal of Andrology
This study aimed to analyze the associations between urinary genistein, daidzein, and equol concentrations and semen parameters in Japanese men exposed to high levels of isoflavone in their diet.
Shoko Konishi   +4 more
doaj   +1 more source

A Simple and Practical Method for Rat Epididymal Sperm Count (Rattus norvegicus)

open access: yesBiology, Medicine & Natural Product Chemistry, 2015
Sperm sample from epididymal source can be determined its number using minimal amount of equipment. These method will aid researcher and practitioner in sperm quality analysis to determined sperm number rapidly and practically.
Muhammad Ja’far Luthfi
doaj   +1 more source

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes

open access: yesAdvanced Science, EarlyView.
eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu   +12 more
wiley   +1 more source

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