Results 71 to 80 of about 2,405,716 (326)

Impairment of spermatogenesis and sperm motility by the high-fat diet-induced dysbiosis of gut microbes

Gut, 2020
Objective High-fat diet (HFD)-induced metabolic disorders can lead to impaired sperm production. We aim to investigate if HFD-induced gut microbiota dysbiosis can functionally influence spermatogenesis and sperm motility.
Ning Ding, Xin Zhang, Xue-Di Zhang, Jun Jing, Shang-Shang Liu, Yun-Ping Mu, Li-Li Peng, Yun-Jing Yan, Geng-Miao Xiao, Xinyun Bi, Hao-Jun Chen, Fanghong Li, B. Yao, A. Zhao   +13 more
semanticscholar   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Urinary isoflavone concentrations and semen parameters of Japanese men seeking fertility treatment

Asian Journal of Andrology
This study aimed to analyze the associations between urinary genistein, daidzein, and equol concentrations and semen parameters in Japanese men exposed to high levels of isoflavone in their diet.
Shoko Konishi, Yuki Mizuno, Kazumitsu Yamasaki, Masahiro Uchida, Teruaki Iwamoto   +4 more
doaj   +1 more source

A Simple and Practical Method for Rat Epididymal Sperm Count (Rattus norvegicus)

Biology, Medicine & Natural Product Chemistry, 2015
Sperm sample from epididymal source can be determined its number using minimal amount of equipment. These method will aid researcher and practitioner in sperm quality analysis to determined sperm number rapidly and practically.
Muhammad Ja’far Luthfi
doaj   +1 more source

Genetic variance and genotype reaction norms in response to larval food manipulation for a trait important in scorpionfly sperm competition. [PDF]

, 2008
Engqvist L. Genetic variance and genotype reaction norms in response to larval food manipulation for a trait important in scorpionfly sperm competition. Functional Ecology. 2008;22(1):070915213639001-???Sperm competition is an important attribute of many
L. Engqvist, Engqvist, Leif ; https://orcid.org/   +1 more
core   +1 more source

One‐Step Induction of Oogonia‐Like and Pro‐Spermatogonia‐Like Cells From Porcine Pluripotent Stem Cells

Advanced Science, EarlyView.
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He, Liang Zhong, Tianzhi Chen, Yaxuan Yan, Xinze Chen, Runbo Li, Yingjie Wang, Yadi Teng, Minglei Zhi, Meng Wang, Jinying Zhang, Fan Zhao, Dengfeng Gao, Suying Cao, Jianyong Han   +14 more
wiley   +1 more source

Habitat‐Specific Design Strategies for Untethered Soft Robots

Advanced Science, EarlyView.
Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li, Zhikun Miao, Tuck‐Whye Wong, Tiefeng Li   +3 more
wiley   +1 more source

Multivariate analysis to predict letrozole efficacy in improving sperm count of non-obstructive azoospermic and cryptozoospermic patients: a pilot study.

Asian Journal of Andrology, 2013
We tested the hypothesis that letrozole increases sperm count in non-obstructive azoospermic or cryptozoospermic patients with a testosterone (T)/17-beta-2-oestradiol (E2) ratio
G. Cavallini, G. Biagiotti, Elisa Bolzon
semanticscholar   +1 more source

Male scorpionflies assess the amount of rival sperm transferred by females' previous mates [PDF]

, 2007
Engqvist L. Male scorpionflies assess the amount of rival sperm transferred by females' previous mates. Evolution. 2007;61(6):1489-1494.Theory predicts that when sperm compete numerically, selection will favor males who vary the number of sperm they ...
Engqvist, Leif ; https://orcid.org/
core   +1 more source

LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription

Advanced Science, EarlyView.
FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang, BingJie Rui, GuangHai Rui, YiNan Duan, Ji Hyang Kim   +4 more
wiley   +1 more source