Results 261 to 270 of about 103,424 (339)

Ascorbic acid 2‐glucoside improves survival, quality, and fertility of frozen‐thawed C57Bl/6J and C57Bl/6N mouse spermatozoa

open access: yesAndrology, EarlyView.
Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa   +2 more
wiley   +1 more source

Rapid detection of mouse spermatogenic defects by testicular cellular composition analysis via enhanced deep learning model

open access: yesAndrology, EarlyView.
Abstract Background Histological analysis of the testicular sections is paramount in infertility research but tedious and often requires months of training and practice. Objectives Establish an expeditious histopathological analysis of mutant mice testicular sections stained with commonly available hematoxylin and eosin (H&E) via enhanced deep learning
Nianfei Ao   +11 more
wiley   +1 more source

Machine learning‐based classification of varicocoele grading: A promising approach for diagnosis and treatment optimization

open access: yesAndrology, EarlyView.
Abstract Background Varicocoele is a correctable cause of male infertility. Although physical examination is still being used in diagnosis and grading, it gives conflicting results when compared to ultrasonography‐based varicocoele grading. Objectives We aimed to develop a multi‐class machine learning model for the grading of varicocoeles based on ...
Mehmet Vehbi Kayra   +6 more
wiley   +1 more source

Cpne1 deficiency preserves sperm motility under Ca2+ channel blockade. [PDF]

open access: yesJ Reprod Dev
Xie Q   +18 more
europepmc   +1 more source

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

open access: yesAndrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert   +10 more
wiley   +1 more source

Benchmarks defining high‐quality sperm in the common marmoset (Callithrix jacchus)

open access: yesAndrology, EarlyView.
Abstract Background Common marmosets (Callithrix jacchus) are increasingly recognized as valuable nonhuman primates (NHPs) for biomedical research due to their small size and short reproductive cycle and lifespan relative to other NHP species. Maximizing the utility of captive research marmosets, including genetically manipulated animals, will require ...
Niloofar Sadeghi   +4 more
wiley   +1 more source

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