Results 51 to 60 of about 66,025 (308)
Advanced Science, EarlyView.The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang +23 more
wiley +1 more source
Role of oxidative stress and antioxidants in domestic and non-domestic cat spermatozoa [PDF]
, 2010 Living cells, including spermatozoa, stored under aerobic conditions require oxygen to support their normal metabolism. Excessive levels of metabolites (reactive oxygen species; ROS) can cause cell damage or lipid peroxidation.
Thuwanut, Paweena
core
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Advanced Science, EarlyView.Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality [PDF]
Iranian Journal of Reproductive Medicine, 2012 Background: Sperm cells extracted from testes (TESE) have poor chromatin quality and motility. Various substances are used in the laboratory to increase sperm motility and improve the ART outcomes; however, there are few research which considered ...
Elham Aliabadi +5 more
doaj
Jurnal Ternak Tropika, 2017 Data were collected from April to Mei 2017 in Singosari National Artificial Insemination Center. The purpose of this research was to examined the correlation between scrotal circumference with semen volume, sperm concentration and motility on the Bali ...
Deny Julio Saputra +2 more
doaj +1 more source
Advanced Science, EarlyView.Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
Lowering Sperm Dose Rates in Frozen Semen for Bovine Artificial Breeding [PDF]
, 2007 The New Zealand Dairy industry relies on artificial breeding to produce high genetic merit replacement stock. Proven bull semen is extended and preserved as either ambient temperature product or as frozen doses.
Pitt, Colin John
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Kufa Journal for Nursing Sciences, 2017 Objective: This study aimed to determine the relationship between the addition of Glutathione to sperm freezing medium and cryosurvival rate of sperm motility and viability in asthenozoospermic patients.
Hisham Q. Mohammad Al-Nowainy
doaj +1 more source
The effect of various air pollution and participants' age on semen quality in southern Taiwan
Taiwanese Journal of Obstetrics & Gynecology, 2023 Objective: This study aimed to investigate the association between semen quality and air pollution in southern Taiwan. Materials and methods: In this retrospective study, 4338 males aged 21–70 years were recruited between 2001 and 2018 from a ...
Hao-Ting Lien +3 more
doaj +1 more source
Advanced Science, EarlyView.This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao +13 more
wiley +1 more source