Results 51 to 60 of about 226,100 (242)

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality [PDF]

Iranian Journal of Reproductive Medicine, 2012
Background: Sperm cells extracted from testes (TESE) have poor chromatin quality and motility. Various substances are used in the laboratory to increase sperm motility and improve the ART outcomes; however, there are few research which considered ...
Elham Aliabadi, Malek Soleimani Mehranjani, Zahra Borzoei, Tahereh Talaei-Khozani, Hossein Mirkhani, Hamed Tabesh   +5 more
doaj  

Korelasi Antara Lingkar Skrotum Dengan Volume Semen, Konsentrasi Dan Motilitas Spermatozoa Pejantan Sapi Bali

Jurnal Ternak Tropika, 2017
Data were collected from April to Mei 2017 in Singosari National Artificial Insemination Center. The purpose of this research was to examined the correlation between scrotal circumference with semen volume, sperm concentration and motility on the Bali ...
Deny Julio Saputra, Moch Nur Ihsan, Nur Isnaini   +2 more
doaj   +1 more source

The effect of various air pollution and participants' age on semen quality in southern Taiwan

Taiwanese Journal of Obstetrics & Gynecology, 2023
Objective: This study aimed to investigate the association between semen quality and air pollution in southern Taiwan. Materials and methods: In this retrospective study, 4338 males aged 21–70 years were recruited between 2001 and 2018 from a ...
Hao-Ting Lien, Ni-Chin Tsai, Yu-Ju Lin, Kuo-Chung Lan   +3 more
doaj   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Relationship between The Addition of Glutathione to Sperm Freezing Medium and Cryosurvival Rate of Sperm Motility and Viability in Asthenozoospermic Patients

Kufa Journal for Nursing Sciences, 2017
Objective: This study aimed to determine the relationship between the addition of Glutathione to sperm freezing medium and cryosurvival rate of sperm motility and viability in asthenozoospermic patients.
Hisham Q. Mohammad Al-Nowainy
doaj   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Correlative Study of Sperm Motility and Mitochondrial Membrane Potential by Fluorescent Staining: First Application in Iraqi Centers [PDF]

Al-Anbar Medical Journal
Background: Sperm motility is an essential factor in ensuring the fertility of males. Sperm mitochondria play a significant role in the generation of energy as well as the metabolism of sperm.
Thaer Farhan
doaj   +1 more source

Detection of Plasma Membrane Alpha Enolase (ENO1) and Its Relationship with Sperm Quality of Bali Cattle

Tropical Animal Science Journal, 2023
Bali cattle are the indigenous cattle well known attributed to their high fertility. Various proteomes in sperm are substances that can determine sperm quality and fertility. One of which is alpha enolase (ENO1).
T. Sumarsono, I. Supriatna, M. A. Setiadi, M. Agil, B. Purwantara   +4 more
doaj   +1 more source