Glycoprotein 88 (GP88) is a secreted biomarker that is overexpressed in various cancers, neurological diseases such as Alzheimer's and Dementia, and inflammatory disorders. A disposable, rapid testing device for GP88 detection provides immediate marker‐level results, helping doctors monitor disease progression and therapy effectiveness. When optimized,
Elham Rezaee +2 more
wiley +1 more source
Evaluation of Predicting Factors Affecting Sperm Retrieval in Patients with Klinefelter Syndrome: A Prospective Study. [PDF]
Aliakbari F +7 more
europepmc +1 more source
Sperm retrieval from patients with nonmosaic Klinefelter’s syndrome by semen cytology examination
Yize Jiang +6 more
openalex +1 more source
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
Testicular mapping-guided sperm retrieval vs. upfront microTESE in non-obstructive azoospermia: a comparison of sperm retrieval, pregnancy and live-birth rates. [PDF]
Kapadia AA +9 more
europepmc +1 more source
Evaluating the Predictive Value of Diagnostic Testicular Biopsy for Sperm Retrieval Outcomes in Men with Non-Obstructive Azoospermia. [PDF]
Kaltsas A +9 more
europepmc +1 more source
Global Diversification Rates of Ferns Across Spatial and Climatic Gradients
Diversification rates of fern genera across the phylogeny. Abstract Geographic patterns of diversity in any group of plants are the result of the interplay of environmental conditions and the evolutionary dynamics of the respective plant group. Here, the geographic distribution of current mean diversification rates (MDR) is explored at the genus level ...
Hong Qian, Michael Kessler, Shenhua Qian
wiley +1 more source
Sperm retrieval in adolescent males with Klinefelter syndrome: medical and ethical issues [PDF]
Alan D. Rogol, Niels E. Skakkebæk
openalex +1 more source
TDP‐43 hyperphosphorylation occurs in neurodegenerative diseases, however, it is not a driver of TDP‐43 aggregation, but enhances TDP‐43 solubility, suggesting that TDP‐43 hyperphosphorylation is protective. Toxicity may arise from a broader phosphorylation‐driven cellular pathway disruption.
Simone Mosna, Dorothee Dormann
wiley +1 more source
Sperm retrieval, fertilization rates, and clinical outcomes of infertile men with Y chromosome microdeletion A retrospective cohort study. [PDF]
Baffa J +5 more
europepmc +1 more source

