Results 101 to 110 of about 168,606 (377)

Hi‐LabSpermTracking: A Novel and High‐Quality Sperm Tracking Dataset with an Advanced Ensemble Detection and Tracking Approach for Real‐World Clinical Scenarios

Advanced Intelligent Systems, EarlyView.
This study presents Hi‐LabSpermTracking, a long‐duration, expert‐annotated sperm motility dataset for detection and tracking. It evaluates You Only Look Once version 8, Real‐Time Detection Transformer, and Simple Online and Realtime Tracking with a Deep Association Metric in three scenarios. The mean ensemble method improves tracking performance. Sperm
Abdulsamet Aktas, Gorkem Serbes, Hakkı Uzun, Merve Huner Yigit, Nizamettin Aydin, Hamza Osman Ilhan   +5 more
wiley   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini, Guilherme Pinn, Thainá Vilella, Maria I. Melaragno, Mariana Moysés‐Oliveira, Luciano Pompei, Rare Genomes Project Consortium, Bianca Bianco, Caio P. Barbosa   +8 more
wiley   +1 more source

50 years of spermatogenesis: Sertoli cells and their interactions with germ cells

Biology of Reproduction, 2018
The complex morphology of the Sertoli cells and their interactions with germ cells has been a focus of investigators since they were first described by Enrico Sertoli. In the past 50 years, information on Sertoli cells has transcended morphology alone to
M. Griswold
semanticscholar   +1 more source

A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]

, 2015
Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco, DE ROOIJ, DIRK GIJSBERT, Di Cecca, Stefano, DI GIACOMO, Monica, DI SIENA, Sara, Faieta, Monica, Luchetti, Andrea, Murdocca, Michela, Pellegrini, Manuela, Rossi, Pellegrino   +9 more
core   +3 more sources

The role of Musashi protein in spermatogenesis and male infertility

Fiyz̤, 2019
Background: Inactivation of transcription occurs during two phases of spermatogenesis. First, in spermatocytes entering the primary meiosis and the second in round and elongating spermatids.
Zohreh Talebi-Yazdabadi , Kianoush Dormiani , Mahboobeh Forouzanfar, Liana Lachinani , Marzieh Tavalaee , Mohammad Hossein Nasr- Esfahani   +5 more
doaj  

In vitro spermatogenesis: A century‐long research journey, still half way around

Reproductive Medicine and Biology, 2018
Background Spermatogenesis is one of the most complicated cellular differentiation processes in a body. Researchers struggled to find and develop a micro‐environmental condition that can support the process in vitro.
Mitsuru Komeya, Takuya Sato, Takehiko Ogawa   +2 more
doaj   +1 more source

Genomic Evaluation of Recombination in Small Highly Inbred Beef Cattle Populations

Animal Research and One Health, EarlyView.
The study characterizes recombination in small beef cattle populations, revealing higher rates in CGC composites compared to inbred Line 1 Herefords. It identifies significant SNP associations linked to recombination across various autosomes, highlighting complex polygenic influences, with implications for genetic diversity and breeding strategies ...
E. Hay, A. S. Ling
wiley   +1 more source

The Drosophila Citrate Lyase Is Required for Cell Division during Spermatogenesis [PDF]

, 2020
The Drosophila melanogaster DmATPCL gene encodes for the human ATP Citrate Lyase (ACL) ortholog, a metabolic enzyme that from citrate generates glucose-derived Acetyl-CoA, which fuels central biochemical reactions such as the synthesis of fatty acids ...
Bucciarelli, Elisabetta, Cenci, Giovanni, Cipressa, Francesca, Di Giorgio, Maria Laura, Manzi, Diana, Morciano, Patrizia, Porrazzo, Antonella, Rong, Yikang S, Saraniero, Sara   +8 more
core   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

Identification and Characterization of Xlr5c as a Novel Nuclear Localization Protein in Mouse Germ Cells. [PDF]

PLoS ONE, 2015
Spermatogenesis is the complex process by which diploid stem cells generate haploid germ cells in gamete production. Members of the Xlr (X-chromosome linked, lymphocyte regulated) superfamily play essential roles in spermatogenesis.
Xin-Jie Zhuang, Wen-hao Tang, Chang-yu Liu, Jin-liang Zhu, Xue Feng, Jie Yan, Ying Lian, Ping Liu, Jie Qiao   +8 more
doaj   +1 more source