Results 101 to 110 of about 66,364 (295)

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Comprehensive diagnostic and therapeutic approach to male factor infertility aimed at natural fertility: A multicentric retrospective cohort study

Andrology, EarlyView.
Abstract Background In infertile couples whose male partner has alterations in semen parameters frequently, a comprehensive andrological approach is lacking and approximately 30–50% are classified as idiopathic infertility. These couples are often directly addressed to assisted reproduction techniques (ARTs).
Giuseppe Grande, Andrea Garolla, Andrea Graziani, Anna Laura Astorri, Maria Vittoria Cammarota, Annamaria Merola, Maria Pia Polidori, Emanuela Lulli, Enrico Busato, Francesco Pesce, Giuseppina Pompa, Alfredo Pontecorvi, Domenico Milardi, Alberto Ferlin   +13 more
wiley   +1 more source

Spermatogenesis in Marsilia [PDF]

Botanical Gazette, 1914
1. In the first spermatogenous mitosis there is present at each spindle pole a dense region with radiations, but no centrosome. 2.
openaire   +2 more sources

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

First application of three‐dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology

Andrology, EarlyView.
Abstract Background Testicular tumors are among the most frequently diagnosed cancers in young men. The consequences of this diagnosis are orchiectomies, severely restricting fertility. For these young patients, a comprehensive diagnostics would be desirable, achieving a refined diagnosis and improved therapeutic patient stratification.
Diana Pinkert‐Leetsch, Ahmad Kareem, Simon F. Merz, Marc Teckentrup, Alexander Fichtner, Felix Bremmer, Jeannine Missbach‐Guentner   +6 more
wiley   +1 more source

Development of the membrane ceiling method for in vitro spermatogenesis

Scientific Reports
Spermatogenesis is one of the most complex processes of cell differentiation and its failure is a major cause of male infertility. Therefore, a proper model that recapitulates spermatogenesis in vitro has been long sought out for basic and clinical ...
Maki Kamoshita, Hiroki Shirai, Hiroko Nakamura, Tetsuya Kishimoto, Yuki Hatanaka, Daisuke Mashiko, Katsuhiro Esashika, Jingjing Yang, Satoshi Yamasaki, Takehiko Ogawa, Hiroshi Kimura, Masahito Ikawa   +11 more
doaj   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Reproductive functions and fertility preservation in men with sickle cell disease

Andrology, EarlyView.
Abstract Background Sickle cell disease (SCD) is a prevalent hereditary disorder with significant morbidity, including potential impacts on male fertility. This study aims to evaluate the semen parameters in men with SCD and assess the outcomes of fertility preservation strategies.
Clarisse Leblanc, Nathalie Sermondade, Diane Rivet‐Danon, Ludmilla Aworet‐Ogouma, Anna Ly, Guillaume Bachelot, Françoise Lionnet, Aline Santin, Anne‐Gael Cordier, Kamila Kolanska, Rachel Lévy, Isabelle Berthaut, Charlotte Dupont   +12 more
wiley   +1 more source

Impact of age at first visit on glycolipid metabolism, bone metabolism, and fertility potential in patients with Klinefelter syndrome

Andrology, EarlyView.
Abstract Background Classic Klinefelter syndrome (KS) is characterized by one extra X chromosome (47, XXY), leading to hypergonadotropic hypogonadism and higher risk of alterations in glycolipid homeostasis, cardiovascular diseases, and low bone mineral density. Most frequently, KS is diagnosed in adulthood because of infertility.
Giordana Ferraioli, Andrea Graziani, Noemi Sagone, Andrea Di Nisio, Massimo Iafrate, Fabrizio Dal Moro, Alberto Ferlin, Andrea Garolla   +7 more
wiley   +1 more source

A Review on Application of Three Dimensional Culture and Testicular Scaffolds to Induction of in-Vitro Spermatogenesis

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Induction of in vitro spermatogenesis can be useful for infertility treatment in azoospermic patients and those undergoing chemotherapy. Different culture systems have been used to achieve this goal. This review study was performed with the
Nasrin Majidi Gharenaz, Mansoureh Movahedin, Samiyeh Majidi, Zohreh Mazaheri   +3 more
doaj