Results 91 to 100 of about 90,893 (356)

SPARK: A webserver for comprehensive search and analysis of testicular single‐cell transcriptomic data covering full lifecycle and pathology

iMetaOmics, EarlyView.
SPARK is an interactive platform hosting 189,232 human testicular single‐cell transcriptomes across normal and infertile conditions. It enables automated, code‐free analysis and visualization, providing a powerful resource to explore cellular and molecular dynamics in male reproduction and infertility.
Lina Cui, Xiaojian Lu, Hui Cai, Ziyan Zhuang, Yifei Guo, Qiaoling Jiang, Zhe Zhang, Hui Jiang, Xiaoyan Wang, Jingtao Guo   +9 more
wiley   +1 more source

Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis.

, 2005
Chromosomes are highly organized and compartmentalized in cell nuclei. The analysis of their position is a powerful way to monitor genome organization in different cell types and states.
Foster, H, Bridger, JM, Foster, Helen A., Abeydeera, Lalantha R., Bridger, Joanna M., Griffin, DK, Abeydeera, L, Griffin, Darren K.   +7 more
core   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Transcriptome sequencing reveals the characteristics of spermatogenesis and testis development in Amphioctopus fangsiao

Aquaculture Reports
Spermatogenesis is the production of spermatozoa by the testes, a process that is associated with reproduction in males. Amphioctopus fangsiao is an economically important species from the northern coast of China, and little research has been done on ...
Yu Jiang, Xiaojie Sun, Zexin Huang, Zan Li, Xiaohui Xu, Weijun Wang, Guohua Sun, Yan Li, Bin Li, Yanwei Feng, Jianmin Yang   +10 more
doaj   +1 more source

Zebrafish dmrta2 Regulates the Expression of cdkn2c in Spermatogenesis in the Adult Testis

, 2013
The exact function of the doublesex and mab-3 related transcription factor-like family a2 gene (dmrta2) has remained largely unknown possibly because of its functional redundancy with dmrta1 in most vertebrates.
Xia, Wei, Gui, JF (reprint author), Chinese Acad Sci, Grad Sch, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan, Peoples R China., Zohar, Yonathan, Gui, Jian-Fang, Xu, Shan   +4 more
core   +1 more source

In Vitro Spermatogenesis

, 2022
In vitro spermatogenesis (IVS) englobes numerous culture techniques that range from single cell expansion and differentiation protocols to the 3D reconstruction of an entire artificial testis all aimed at reproducing the entire spermatogenesis process in
Wyns, Christine, Christine Wyns, Kanbar, Marc, Marc Kanbar   +3 more
core   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

An update on the potential for male contraception : emerging options

, 2013
The human population continues to grow and is estimated to rise to 10.1 billion by the end of the century. Therefore, there is still an unmet need for safe and highly effective contraceptive options for both men and women.
Nimmo, Natalie, Gebril, Ayman M, Alsaadi, Manal, Ferro, Valerie, Mullen, Alexander, Garside, Deborah A   +5 more
core   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

E3 Siah ubiquitin ligase regulates dichotomous spermatogenesis in Sitotroga cerealella

Frontiers in Cell and Developmental Biology
Spermatogenesis in Lepidoptera holds significant importance due to its unique process of dichotomous spermatogenesis, yielding eupyrene and apyrene spermatozoa through a complex molecular mechanism.
Sakhawat Shah, Chun-Mei Shi, Karam Khamis Elgizawy, Wen-Han Yan, Gang Wu, Xiao-Ping Wang, Feng-Lian Yang   +6 more
doaj   +1 more source