Results 101 to 110 of about 90,893 (356)

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice   +8 more
wiley   +1 more source

Spermatogenesis

open access: yes
Spermatogenesis is an extraordinarily complex cellular reorganization producing distinctive elongated haploid gametes. Successful spermatogenesis is critical to reproduction and species survival, and sperm, and the genes expressed in them, evolve rapidly.
White-Cooper, Helen   +2 more
core   +2 more sources

CWF19L2 is Essential for Male Fertility and Spermatogenesis by Regulating Alternative Splicing

open access: yesAdvanced Science
The progression of spermatogenesis along specific developmental trajectories depends on the coordinated regulation of pre‐mRNA alternative splicing (AS) at the post‐transcriptional level.
Shiyu Wang   +15 more
doaj   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

ROLE OF THE ENDOCANNABINOID SYSTEM IN SPERMATOGENESIS: SYSTEMS BIOLOGY APPROACH

open access: yes, 2014
The spermatogenesis is a complex process that requires the differentiation of male gametes within the male genital tract. It involves a series of cellular events including mitosis, meiosis, cell migration, apoptosis, and differentiation of diploid germ
BARBONI, Barbara   +4 more
core  

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

open access: yesPediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang   +7 more
wiley   +1 more source

Induction of Spermatogenesis and Its Predictors in Men with Prepubertal-Onset Hypogonadotropic Hypogonadism Undergoing Gonadotropin Therapy

open access: yesThe World Journal of Men's Health
Purpose: To evaluate the outcomes of gonadotropin therapy (GT) using human chorionic gonadotropin (hCG) and recombinant follicle-stimulating hormone (rFSH) for inducing spermatogenesis in men with prepubertal-onset hypogonadotropic hypogonadism (HH ...
Min Chul Cho, Hohyun Lee, Soo Woong Kim
doaj   +1 more source

Impacts of morphine addiction on spermatogenesis in rats

open access: yesIranian Journal of Reproductive Medicine, 2016
Background: There are numerous investigations on wide range of issues that disrupt regulatory spermatogenesis, individuals who are exposed to drug abuse faced infertility and immature spermatogenesis. Objective: The aim of this study was to evaluate the
Nasrin Takzare   +6 more
doaj  

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia   +7 more
wiley   +1 more source

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