Results 201 to 210 of about 102,741 (261)

Lactate inhibits glucose‐induced zigzag motility and enhances linear motility in bull spermatozoa by suppressing glycolysis

Andrology, Volume 14, Issue 3, Page 933-945, March 2026.
Abstract Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility is a prerequisite for fertilization. The preference of metabolic pathways depends on substrate availability which controls sperm motility. However,
Md Faizul Hossain Miraz, Takahiro Yamanaka, Shahrina Akter, Masanori Koyago, Masayuki Shimada   +4 more
wiley   +1 more source

Fertility Outcomes in Men with Nonobstructive Azoospermia Due to Hypogonadotropic Hypogonadism After Gonadotropin Therapy. [PDF]

J Clin Med
Zachariou A, Zikopoulos A, Markou E, Koukos S, Daligaros G, Skouros S, Dimitriadis F, Chrisofos M, Sofikitis N, Kaltsas A.   +9 more
europepmc   +1 more source

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, Volume 14, Issue 3, Page 747-765, March 2026.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source

Obesity impairs spermatogenesis via Leydig cell ferroptosis induced by liver-derived exosomal miR-122-5p. [PDF]

Commun Biol
Wang N, Zhang B, Chen T, Zong J, He G, Cao M, Wang Y, Chen X, Luo Y, Shen C, Sun Y, Li C, Zhou X.   +12 more
europepmc   +1 more source

INSL3 Expression in Leydig Cells is a Biomarker for Immunocastration in Boars: Transcriptional Evidence

Andrology, Volume 14, Issue 3, Page 782-795, March 2026.
ABSTRACT Background Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. Objectives It was hypothesized that the timing of gonadotropin‐releasing hormone (GnRH) suppression by immunocastration ...
Nina Batorek Lukač, Martin Škrlep, Klavdija Poklukar, Petra Ferjan, Volker Stefanski, Gregor Fazarinc, Milka Vrecl   +6 more
wiley   +1 more source

Nicotinamide mononucleotide improves spermatogenesis in aluminium-exposed mice by inhibiting NLRP3-mediated pyroptosis. [PDF]

PLoS One
Nong W, Huang Q, Dou S, Wei Y, Song Y, Wang J, Lei X, Yang F, He L.   +8 more
europepmc   +1 more source

Subchronic Exposure to Aripiprazole Subtly Impacts on Rodents' Sperm Quality and Fertility

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Aripiprazole, a third‐generation antidepressant/antipsychotic drug, acts on serotonergic and dopaminergic receptors and is widely prescribed for mental disorders, such as depression and schizophrenia. Studies indicate that this class of drugs can impact directly on sperm quality and fertility.
Maria Joana Nogueira de Moura, Renata Gleysiane Sousa de Felix, Aline Gabriele Gomes da Silva, Ana Beatriz Silva Angelo, Caio César Araújo dos Santos, Artemia Kelly Holanda Pereira, Michelly Fernandes de Macedo, Cibele dos Santos dos Borges   +7 more
wiley   +1 more source

Sertoli cells as a hub in testicular development and male reproductive. [PDF]

Front Cell Dev Biol
Feng X, Tian J, Han S, Wen F, Li Y, Zhang S, Ouyang L, Hu Z, Chen X, Hu J.   +9 more
europepmc   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, Volume 59, Issue 3, March 2026.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

Nanopore Sequencing Technology Reveals the Transcriptional Expression Characteristics of Male Pig's Testes Before and After Sexual Maturity. [PDF]

Genes (Basel)
Yang Y, Chen S, Hao Z, Zhou T, Guan S, Tan Y, Wang Y, Zhou X, Chen L, Zhao Y, Shen L, Zhu L, Gan M.   +12 more
europepmc   +1 more source