Results 191 to 200 of about 57,423 (263)
ATF4 Is Dispensable for Spermatogenesis but Protective Against ER Stress Under Normal Conditions. [PDF]
Zhang M, Wu Z, Teng Y, Zhu H, Dai P.
europepmc +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Adropin: A New Regulator of Testicular Function-What Do We Know So Far? [PDF]
Muhammed AA, Babiker R.
europepmc +1 more source
The 9th International RASopathies Symposium
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
RNA Interference Targeting Testis-Specific Serine/Threonine Protein Kinase 1 (<i>TSSK1</i>) Gene Triggers Male Infertility in <i>Zeugodacus tau</i>. [PDF]
Huang X, Wen W, Chen S, Zhou Q, Peng W.
europepmc +1 more source
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell +13 more
wiley +1 more source
Immediate spermatogenesis assessment after testicular tissue retrieval for azoospermic males using touch print smear. [PDF]
Hsu CH +6 more
europepmc +1 more source
We evaluated adaptation to torpor and hibernation in the genus Dromiciops by comparing it with both torpid and non‐torpid marsupials, and investigated divergent selection signals between its two species. For the ancestral node, we identified positive selection in the genes PFKFB2, LAMP3, OTX1, and RAPSN, alongside an enrichment of pathways potentially ...
Elisa Gonzalez‐Ugalde +7 more
wiley +1 more source
Gut microbiota induces dysspermatogenesis via microbial-derived phenylacetylglycine in Ggt1-deficient mice. [PDF]
Tang J +11 more
europepmc +1 more source
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley +1 more source

