Results 131 to 140 of about 52,517 (253)

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

open access: yesAndrology, Volume 14, Issue 6, Page 1579-1589, September 2026.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda   +7 more
wiley   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

open access: yesAndrology, Volume 14, Issue 6, Page 1636-1646, September 2026.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda   +2 more
wiley   +1 more source

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

open access: yesAndrology, Volume 14, Issue 6, Page 1472-1478, September 2026.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik   +3 more
wiley   +1 more source

Improvement of Mouse Spermatozoa Freezing at −80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

open access: yesAndrology, Volume 14, Issue 6, Page 1647-1655, September 2026.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso   +6 more
wiley   +1 more source

Impact of extended equilibration periods on in vitro post-thaw sperm quality in rams. [PDF]

open access: yesVet Res Commun
Korkmaz F   +7 more
europepmc   +1 more source

Limited Utility of a Test‐Yolk Buffer Semen Extender for Preserving Human Semen Parameters for Use in a Diagnostic Setting

open access: yesAndrology, Volume 14, Issue 6, Page 1701-1711, September 2026.
ABSTRACT Background Identification of a preservation medium that accurately retains semen parameters would be advantageous for men requiring semen analysis by allowing them to produce sperm samples at home rather than on site or even facilitate ‘mail order’ semen analysis.
Alessia Schadwell   +5 more
wiley   +1 more source

Semen Quality in Transgender Individuals Seeking Fertility Preservation

open access: yesAndrology, Volume 14, Issue 6, Page 1771-1776, September 2026.
ABSTRACT Background Transgender individuals assigned male at birth (AMAB) may choose to preserve their fertility prior to starting gender‐affirming hormone therapy (GAHT). However, limited data exist regarding the baseline reproductive and hormonal characteristics of this population before and after GAHT.
Maurizio De Rocco Ponce   +43 more
wiley   +1 more source

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