ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva +13 more
wiley +1 more source
Differential Modulation of Capacitation-Associated Responses in Boar Spermatozoa by In Vitro Capacitation Media: A Kinetic Study. [PDF]
de Mercado E +6 more
europepmc +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Thiram inhibits human sperm motility and capacitation by increasing mitochondrial O<sub>2</sub> <sup>-</sup> and reducing PTK and PAK4 activity at environmental concentrations. [PDF]
Wen Z +6 more
europepmc +1 more source
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao +13 more
wiley +1 more source
Current state of alpaca reproduction: present status and future perspectives of assisted reproductive technologies. [PDF]
Landinez-Aponte J, Wang Z.
europepmc +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
Swadamshtradi rasayana attenuates radiofrequency radiation-induced oxidative stress and improves sperm parameters in Swiss albino mice. [PDF]
Abdul VR +5 more
europepmc +1 more source
ABSTRACT This study aimed to reveal the relationship between experimental varicocele and melatonin levels. Forty adult Wistar albino rats were used in this study. Control (C), Melatonin (M), Varicocele (V), Varicocele+Melatonin (V + M) were planned. Varicocele was created on the first day of the experiment by opening the abdominal area, narrowing the ...
Esra Önal +2 more
wiley +1 more source
The effect of fenugreek (Trigonella foenum-graecum) on stallion spermatozoa motility and vitality in vitro. [PDF]
Vanivska K +10 more
europepmc +1 more source

