Results 211 to 220 of about 93,530 (291)

Effects of Trazodone on Testicular Morphology, Sperm Parameters and Contractility of the Distal Cauda Epididymal Duct in Rats

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva   +13 more
wiley   +1 more source

Differential Modulation of Capacitation-Associated Responses in Boar Spermatozoa by In Vitro Capacitation Media: A Kinetic Study. [PDF]

open access: yesAnimals (Basel)
de Mercado E   +6 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, Volume 600, Issue 17, Page 2564-2578, September 2026.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao   +13 more
wiley   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie   +20 more
wiley   +1 more source

Melatonin Regulates Growth‐Arrest and DNA‐Damage Genes GADD153, GADD45g and GADD34 in Experimental Varicocele

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT This study aimed to reveal the relationship between experimental varicocele and melatonin levels. Forty adult Wistar albino rats were used in this study. Control (C), Melatonin (M), Varicocele (V), Varicocele+Melatonin (V + M) were planned. Varicocele was created on the first day of the experiment by opening the abdominal area, narrowing the ...
Esra Önal   +2 more
wiley   +1 more source

The effect of fenugreek (Trigonella foenum-graecum) on stallion spermatozoa motility and vitality in vitro. [PDF]

open access: yesVet Res Commun
Vanivska K   +10 more
europepmc   +1 more source

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