Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup +12 more
wiley +1 more source
Self-Perceived Health, Comorbidity, and Burden Among Older Family Caregivers of Seniors with Severe Mental Disorders: A Cross-Sectional Study. [PDF]
Gama AC +5 more
europepmc +1 more source
As the hepatic venous pressure gradient (HVPG) remains the current gold standard for diagnosing portal hypertension in cirrhosis, its clinical application is limited by invasiveness, high cost, and restricted availability. Given the urgent need for noninvasive techniques to dynamically monitor portal vein pressure (PVP), contrast‐enhanced ...
Danping Huang +5 more
wiley +1 more source
Catastrophe mechanism and early warning indicators of seepage erosion-induced water inrush in karst cavities. [PDF]
Yuan J, Zhang P, Qian X, Zhang L, Liu Y.
europepmc +1 more source
Outer‐Sphere Tuning of Synthetic Iron–Sulfur Clusters Within Nanoscale Cage Frameworks
Noncovalent encapsulation of a synthetic iron–sulfur cluster within hydrophobic, naphthalenediimide (NDI)‐paneled cages is shown to lead to dramatic changes in the electronic structure and covalency of the Fe─S core. ABSTRACT As atomic‐scale archetypes for multi‐electron transfer, iron–sulfur clusters are compelling candidates for the design of redox ...
Rupal Baliyan +3 more
wiley +1 more source
Virtual ultrasound machine operating in a GHz to MHz frequency range for particle-based biomedical simulations. [PDF]
Čoko U, Potisk T, Praprotnik M.
europepmc +1 more source
A review of numerical methods for flow and transport modeling in the vadose zone
Abstract Accurate modeling of subsurface flow and transport processes in the vadose zone, governed by the Richards equation and advection‐dispersion equation, respectively, poses major numerical challenges due to the strong nonlinearity of the governing partial differential equations, spatial heterogeneity and anisotropy of the media parameters, and ...
Shruti Jain, Saumava Dey, B. R. Chahar
wiley +1 more source
Synphilin-1 Is Essential for Cytoskeletal Integrity of Brain Ventricular Cilia and Mitochondrial Proteostasis. [PDF]
Farhoud M +16 more
europepmc +1 more source
Abstract This study presents a survey of high‐latitude ionospheric scintillation using GNSS radio occultation (RO) data from the PlanetiQ satellite. The analysis examines 483 high‐latitude RO tracks between January and May 2023, with 371 tracks exhibiting scintillation events.
Margaret W. Chen +6 more
wiley +1 more source
Mediation of sphingolipid metabolism on the relationship between human nitrosamines exposure and esophageal cancer risk. [PDF]
Zhao C +15 more
europepmc +1 more source

