Results 91 to 100 of about 2,148,448 (284)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Sliced rotated sphere packing designs
, 2017 Space-filling designs are popular choices for computer experiments. A sliced design is a design that can be partitioned into several subdesigns. We propose a new type of sliced space-filling design called sliced rotated sphere packing designs. Their full
He, Xu
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Trials, 2018 Background Institutional review boards must guarantee the ethical acceptability of a randomized controlled trial before it is conducted. However, some may regard an unbalanced randomization ratio as reflecting an absence of uncertainty between the groups
Clarisse Dibao-Dina +2 more
doaj +1 more source
Sphere bundles over spheres and H-spaces
Topology, 1969 In this paper the authors answer negatively the following question of J. F. Adams and I. M. James. Can the total space of a 7-sphere bundle over either the 11-sphere or the 15-sphere be an \(H\)-space? This result implies that the quaternionic Stiefel manifold \(W_{3,2}\) and the octonionic Stiefel manifold \(Y_{2,2}\) can not be \(H\)-spaces.
Douglas, Roy R., Sigrist, Frano̧is
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Turbulent shear flow downstream of a sphere with and without an o-ring located over a plane boundary
EPJ Web of Conferences, 2012 Flow-structure interaction of separated shear flow from the sphere and a flat plate was investigated by using dye visualization and the particle image velocimetry technique. Later, a passive control method was applied with 2mm oring located on the sphere
Sahin Besir +4 more
doaj +1 more source
Haddock et le contenu alcoolique de l’aventure
Carnets, 2020 This abstract examines in Les Aventures de Tintin the morphology of the heroic figure composed by two characters, Tintin and Haddock, and aims to describe the tension that fosters it.
Cristina Álvares
doaj +1 more source
Optics Express, 2015 We present a generalized Poincaré sphere (G sphere) and generalized Stokes parameters (G parameters), as a geometric representation, which unifies the descriptors of a variety of vector fields. Unlike the standard Poincaré sphere, the radial dimension in the G sphere is not used to describe the partially polarized field.
Zhi-Cheng, Ren +6 more
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source