Results 111 to 120 of about 735,551 (295)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Joint design of twin-antenna assisted space-time multilevel sphere packing aided coded modulation
, 2006 A new multilevel coding (MLC) scheme invoking sphere packing (SP) modulation is proposed, where the SP arrangement is jointly designed with a space time block code (STBC) for the sake of attaining an additional space diversity gain.
Alamri, O., Tee, R.Y.S., Hanzo, L.
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Health and Quality of Life Outcomes, 2018 Background Patients with prostate cancer (PC) may be ready to make trade-offs between their quantity and their quality of life. For instance, elderly patients may prefer the absence of treatment if it is associated with a low-risk of disease progression,
Yohann Foucher +5 more
doaj +1 more source
Public Sphere as Democratic Sphere
Issues in Social Science, 2018 Political public space is more conflicted and stressed. Process of black-balling other actors is dominant here. Other civilian public spaces mean mutual learning and opinion improvement. These two spaces try to affect each other. Civilian public spaces try to affect political public space with political discourses.
Ziba Faeedfar, Yasin Lotfata
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ekonomika Nauki, 2018 The article describes a methodical approach to the development of Web of Science and Scopus rubricators-adapter in the system of priorities of the Strategy of scientific and technological development of the Russian Federation.
S. L. Parfenova +4 more
doaj +1 more source
Gender, Diversity and the European Public Sphere [PDF]
This paper is an exercise in asking new questions from old theories. New questions that lead to new theoretical considerations, and to new ideas for how to design studies and analyze data. The American psychologist Abraham Maslow reputedly said ‘When all
Helene Pristed Nielsen
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source