Results 111 to 120 of about 2,662,283 (378)

Spheres over fields, their entire rational maps and applications

open access: yesPracì Mìžnarodnogo Geometričnogo Centru
The paper summarizes some results on algebraic geometry presence in the homotopy theory. For the homotopy group πm(Sn), denote by πalgm(Sn) its subset of homotopy classes represented by ℝ-entire rational maps Sm→Sn of spheres.
Marek Golasinski
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Low-energy buildings: Bioclimatic improvements appropriate to Belgrade [PDF]

open access: yesArhitektura i Urbanizam, 2006
Buildings consume around 40% of the total world energy and bioclimatic architecture may achieve energy savings for heating and air conditioning purposes.
MiloradoviĆ Nenad
doaj  

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

The SPHERE data center: a reference for high contrast imaging processing [PDF]

open access: yes, 2017
The objective of the SPHERE Data Center is to optimize the scientific return of SPHERE at the VLT, by providing optimized reduction procedures, services to users and publicly available reduced data. This paper describes our motivation, the implementation
Albert, D.   +21 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Hodge Decomposition of Conformal Vector Fields on a Riemannian Manifold and Its Applications

open access: yesMathematics
For a compact Riemannian m-manifold (Mm,g),m>1, endowed with a nontrivial conformal vector field ζ with a conformal factor σ, there is an associated skew-symmetric tensor φ called the associated tensor, and also, ζ admits the Hodge decomposition ζ=ζ¯+∇ρ,
Hanan Alohali   +3 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

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