Results 91 to 100 of about 359,437 (296)

Brachytherapy of intra ocular tumors using ′BARC I-125 Ocu-Prosta seeds′: An Indian experience

Indian Journal of Ophthalmology, 2014
Aim: To report our experience of brachytherapy using ′BARC I-125 Ocu-Prosta seeds′ for the management of intraocular tumors with regard to tumor control, globe preservation visual outcome, and patient survival at Sankara Nethralaya, Chennai, India ...
Vikas Khetan, Lingam Gopal, Mahesh P Shanmugam, Aditi Gupta, Tarun Sharma, Pramod Bhende, Siva Muthukumar, R Subramaniam, Thayalan Kuppuswamy, S K Saxena, Ashutosh Dash   +10 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Successful transportation of human corneal endothelial tissues without cool preservation in varying Indian tropical climatic conditions and in vitro cell expansion using a novel polymer

Indian Journal of Ophthalmology, 2014
Background: Though the transplantation of human corneal endothelial tissue (CET) separated from cadaver cornea is in practice, its transportation has not been reported.
Srinivas K Rao, John Sudhakar, Periyasamy Parikumar, Sundaram Natarajan, Aditya Insaan, Hiroshi Yoshioka, Yuichi Mori, Shigeo Tsukahara, Subramani Baskar, Sadananda Rao Manjunath, Rajappa Senthilkumar, Paramasivam Thamaraikannan, Thangavelu Srinivasan, Senthilkumar Preethy, Samuel J K Abraham   +14 more
doaj   +1 more source

Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids [PDF]

, 2016
Malignant epithelial ovarian cancer (EOC) spheroids high frequently are detected in the malignant ascites of the patients with the extensive peritoneal metastasis of ovarian cancer, which represent a significant obstacle to efficacious treatment ...
Cai, Jun, Jiang, Wen
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The effect of multimedia interventions on the informed consent process for cataract surgery in rural South India

Indian Journal of Ophthalmology, 2014
Context: The provision of ocular surgical interventions for poorer, less educated populations is increasing as a result of increased globalization and outreach.
Abraar Karan, Prashanth Somasundaram, Haben Michael, Aryan Shayegani, Hylton Mayer   +4 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Corneal changes following collagen cross linking and simultaneous topography guided photoablation with collagen cross linking for keratoconus

Indian Journal of Ophthalmology, 2014
Purpose: To compare the outcome of Collagen cross-linking (CXL) with that following topography-guided customized ablation treatment (T-CAT) with simultaneous CXL in eyes with progressive keratoconus.
Prema Padmanabhan, Aishwaryah Radhakrishnan, Abinaya Priya Venkataraman, Nidhi Gupta, Bhaskar Srinivasan   +4 more
doaj   +1 more source

Molecular and functional characterization of cells with stem properties isolated by sphere forming assay from human renal cell carcinoma tissues and cell lines

, 2014
Cancer stem cells (CSC) are a rare subset of malignant cells that constitute a reservoir of tumor‐initiating cells with the ability to both self‐renew and differentiate into bulk tumors. As well as for other tumors, also in Renal Cell Carcinoma (RCC) the identification of CSCs might represent a step toward the development of therapies able to totally ...
openaire   +2 more sources

Divalent Metal Binding Properties of the Methionyl Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2000
The metal-binding properties of the methionyl aminopeptidase from Escherichia coli (MetAP) were investigated. Measurements of catalytic activity as a function of added Co(II) and Fe(II) revealed that maximal enzymatic activity is observed after the ...
Bennett, Brian, Copik, Alicja J., D\u27Souza, Ventris M., Holz, Richard C.   +3 more
core   +1 more source