Results 71 to 80 of about 2,109,763 (264)

Restoration of Radiosensitivity by Soya Isoflavone Genistein is Accomplished by Facilitating DNA Damage Response in Radioresistant Cervical Cancer in vitro

Journal of Radiation and Cancer Research
Context: Enhancing radiotherapeutic efficacy in tumor cells and sparing the normal tissues are major clinical concerns for the betterment of cancer therapy.
Das Salini, Thakur Debanjan, Sengupta Debomita, Mukherjee Sutapa   +3 more
doaj   +1 more source

Challenges in pediatric endothelial keratoplasty

Indian Journal of Ophthalmology, 2014
We performed endothelial keratoplasty (EK) in three eyes of two siblings (2.5 years, male and 3.5 years, female) with congenital hereditary endothelial dystrophy (CHED) and report the intraoperative and postoperative difficulties. Repeated iris prolapse,
Vikas Mittal, Ruchi Mittal
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Ethanol extract of Moringa oliefera prevents in vitro glucose induced cataract on isolated goat eye lens

Indian Journal of Ophthalmology, 2014
Aim of Study: The aim of current work was to evaluate in vitro anticataract potential of Moringa oliefera extract. Materials and Methods: Goat eye lenses were divided into 4 groups; Group served as control, Group II as toxic control, Group III and Group ...
Raghvendra Kurmi, Aditya Ganeshpurkar, Divya Bansal, Abhishek Agnihotri, Nazneen Dubey   +4 more
doaj   +1 more source

Physical principles underlying the floating sphere assay.

, 2022
Forces acting on the bead for the three possible outcomes of the Floating Sphere assay. (A) Bead is floating; (B) bead is partially submerged; (C) bead is completely submerged. Please see the text for details.
Megan Goh (13020861), Uma Jingxin Tay (13020858), Jeralyn Ching Wen Hui (13020864), Prakash Arumugam (303310)   +3 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Lateral-Flow Assay for Rapid Serodiagnosis of Human Leptospirosis [PDF]

, 2001
An assay device for the rapid detection of Leptospira-specific immunoglobulin M (IgM) antibodies in human sera is presented. The sensitivity (85.8%) and specificity (93.6%) of the assay compared well (91.9% agreement) with those of an IgM enzyme-linked ...
Smits, H. L., Kuriakose, M., Abdoel, Theresia H, Gasem, M. Hussein, Sugathan, Sheela, Smits, Henk L., Pujianto, B., Sasaki, David, Sasaki, D., Vestering, Marc, Abdoel, T. H., Kuriakose, Mariamma, Gussenhoven, G. C., Eapen, C. K., Gasem, M. H., Pujianto, Bambang, Yersin, C., Gussenhoven, George C, Sugathan, S., Vestering, M., Yersin, Claude   +20 more
core   +2 more sources

Management of recurrent postoperative fungal endophthalmitis

Indian Journal of Ophthalmology, 2014
Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India.
Anand Vinekar, Mangat R Dogra, Kavitha Avadhani, Vishali Gupta, Amod Gupta, Arunaloke Chakrabarti   +5 more
doaj   +1 more source

Nondestructive Assay of Sphere-Pac Fuel Rods [PDF]

, 1981
Nondestructive assay (NDA) methods were studied for application to sphere-pac fuel with a high gamma ray background. It was decided that the NDA method selected should be capable of measuring total fissile content of each fuel rod as well as determining ...
S.P. Baker, Mack, J. E., P. Angelini, Heck, J. L., J.L. Heck, Baker, S. P., E.J. Allen, J.E. Mack, Allen, E. J., Angelini, P.   +9 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source