Results 1 to 10 of about 2,761 (203)

Citicoline May Effectively Reduce Hard Exudates in Diabetic Retinopathy [PDF]

Biomedicines
Background/Objectives: Diabetic retinopathy (DR) develops from the interplay of vascular, inflammatory, and neurodegenerative processes. Citicoline, a natural compound essential for cell membranes, enhances neurotransmitter levels, has a neuroprotective ...
Martina Tomić, Toma Babić, Tomislav Bulum, Spomenka Ljubić, Tomislav Jukić   +4 more
doaj   +3 more sources

Comparison of the effects of choline alphoscerate and citicoline in patients with dementia disorders: a systematic review and meta-analysis [PDF]

Frontiers in Neurology
BackgroundOver 44 million people worldwide live with dementia, affecting their quality of life and well-being. Choline alphoscerate and citicoline supplements are commonly used to improve cognitive function in dementia patients.
Getu Gamo Sagaro, Getu Gamo Sagaro, Francesco Amenta, Francesco Amenta   +3 more
doaj   +2 more sources

The efficacy of different doses of citicoline in improving the prognosis of patients with acute ischemic stroke based on network meta-analysis [PDF]

Frontiers in Pharmacology
ObjectiveOur group aimed to explore the effect of different dosages of citicoline on ischemic stroke (IS) patients and determine the most appropriate dosage for these patients.MethodsThe databases of PubMed, Cochrane Library, Medline, Web of Science, and
Xu Zhao, Xianhao Huo, Yizhen Meng, Ran Zhao, Xiaozhuo Liu, Jiancheng Chen, Zhiqi Mao, Mei Li   +7 more
doaj   +2 more sources

Citicoline Triggers Proteome Remodeling and Proteostatic Adaptation: Evidence from Shotgun Proteomics [PDF]

Pharmaceutics
Background/Objectives: Citicoline, also known as CDP-choline, is a nootropic agent currently used in the treatment of glaucoma and is undergoing evaluation as a first-line therapy in a multi-center, international, phase III, randomized clinical trial ...
Dario Cavaterra, Sara Giammaria, Irene Pandino, Gabriele Antonio Zingale, Valerio Delli Paoli, Rebecca Fiore, Manuele Michelessi, Gloria Roberti, Carmela Carnevale, Lucia Tanga, Daniela Cazzato, Elisa Peroni, Giuseppe Grasso, Gianluca Manni, Alessio Bocedi, Francesco Oddone, Massimiliano Coletta, Diego Sbardella, Grazia Raffaella Tundo   +18 more
doaj   +2 more sources

Combined citicoline and Cerebrolysin for neuroprotection in traumatic brain injury: a retrospective cohort analysis [PDF]

Frontiers in Neurology
IntroductionSevere traumatic brain injury (sTBI) remains a major cause of long-term disability and mortality worldwide. Beyond the initial mechanical damage, a cascade of secondary injuries involving neuroinflammation, oxidative stress, and ...
Philipp Schlager, Philipp Schlager, Ivan Grgac, Ivan Grgac, Guenther Herzer, Guenther Herzer, Helmut Trimmel, Helmut Trimmel, Helmut Trimmel   +8 more
doaj   +2 more sources

The effect of citicoline administration on visual function improvement in stroke patients at Prof. Dr. Chairuddin Panusunan Lubis Hospital, University of Sumatera Utara, and affiliated network hospitals [PDF]

Frontiers in Medicine
BackgroundVisual disturbances are a common and often debilitating complication following stroke, significantly impairing patients’ functional independence and quality of life. Among various neuroprotective agents, Citicoline (cytidine-5′-diphosphocholine)
Silvia Fransisca, Bobby Ramses Erguna Sitepu, Delfi   +2 more
doaj   +2 more sources

Comparative Effects of BCI-Based Attention Training, Methylphenidate, and Citicoline on Attention and Executive Function in School-Age Children: A Quasi-Experimental Study [PDF]

Medicina
Background and Objectives: Attention-Deficit Hyperactivity Disorder (ADHD) is a neurological condition characterized by cognitive task difficulty, impulsivity, hyperactivity and loss of attention.
Serkan Turan, Remzi Oğulcan Çıray
doaj   +2 more sources

The impact of citicoline on brain mitochondrial dysfunction induced in rats after head irradiation [PDF]

Scientific Reports
Head irradiation is a common treatment for brain cancer; however, it can cause side effects in healthy brain tissue. This study aimed to test whether citicoline administration modulates radiation-induced brain mitochondrial dysfunction in rats.
Nahed Abdel-Aziz, Fatma Rabia Algeda, Shereen M. Shedid   +2 more
doaj   +2 more sources

Effect of oral citicoline therapy on retinal nerve fiber layer and ganglion cell-inner plexiform layer in patients with primary open angle glaucoma [PDF]

International Journal of Ophthalmology, 2022
AIM: To evaluate the short-term effects of oral citicoline therapy on the retinal nerve fiber layer (RNFL) and the macular ganglion cell-inner plexiform layer (mGCIPL) in patients with primary open angle glaucoma (POAG).
Asena Keles Sahin, Hasan Burhanettin Kapti, Aslihan Uzun   +2 more
doaj   +1 more source

Citicoline in acute ischemic stroke: A randomized controlled trial

PLoS ONE, 2022
Introduction Two pharmacological possibilities exist for an acute ischemic stroke (AIS): recanalization of the occluded artery and neuroprotection from ischaemic injury, the latter’s efficacy being debatable. We sought to determine whether administration
Ayush Agarwal, Venugopalan Y. Vishnu, Jyoti Sharma, Rohit Bhatia, Ajay Garg, Sadanand Dwivedi, Ashish Upadhyay, Vinay Goyal, Mamta Bhushan Singh, Anu Gupta, Roopa Rajan, M. V. Padma Srivastava   +11 more
doaj   +2 more sources