Results 11 to 20 of about 2,761 (203)

Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution.

open access: yesPLoS ONE, 2019
PURPOSE:To evaluate the presence and concentration of citicoline and its metabolites (choline, cytidine and uridine) in the vitreous body in human eyes after topical application of an ophthalmic solution of citicoline 2%, in vivo.
Carmela Carnevale   +11 more
doaj   +9 more sources

Role of Citicoline in Patients With Mild Cognitive Impairment

open access: yesNeuroscience Insights, 2023
The term mild cognitive impairment (MCI) defines an intermediate state between normal aging and dementia. Vascular cognitive impairment refers to a decline in cognitive function that is caused by or associated with vascular disease and comprises all the ...
Pedro E Bermejo   +2 more
doaj   +2 more sources

Role of Citicoline in an in vitro AMD model [PDF]

open access: yesAging, 2020
Citicoline is the exogenous form of the nootropic, Cytidine 5'-diphosphate-choline that exerts its neuroprotective effects in the brain as well as in the eye.
Kenney, M Cristina, Nashine, Sonali
core   +5 more sources

Neuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension

open access: yesAntioxidants
Glaucoma is a neurodegenerative disease characterized by the loss of retinal ganglion cells (RGCs), with intraocular pressure (IOP) being its primary risk factor. Despite controlling IOP, the neurodegenerative process often continues.
José A. Matamoros   +14 more
doaj   +2 more sources

Synthesis of process related impurities of Citicoline and Citicoline sodium

open access: yesIndian Journal of Chemistry
304-314Citicoline is the diphosphate ester of cytidine. The said compound is sensitive to chemical atmosphere and exhibits formation of process/degradation impurities.
Kotharkar, Sandeep A   +3 more
core   +2 more sources

Citicoline: A Superior Form of Choline? [PDF]

open access: yesNutrients, 2019
Medicines containing citicoline (cytidine-diphosphocholine) as an active principle have been marketed since the 1970s as nootropic and psychostimulant drugs available on prescription.
Kamil Synoradzki, Paweł Grieb
core   +3 more sources

Citicoline for ischemic stroke: ICTUS trial [PDF]

open access: yesНеврология, нейропсихиатрия, психосоматика, 2012
The paper gives data available in the literature on the use of citicoline in an experimental model of ischemic stroke (IS) and in randomized multicenter placebo-controlled trials.
Vladimir Anatolyevich Parfenov
doaj   +2 more sources

Effect of citicoline on blood pressure variability [PDF]

open access: yesНеврология, нейропсихиатрия, психосоматика, 2014
The authors give the results of their investigation dealing with citicoline therapy in patients with hypertension and cognitive impairments.Objective: to determine the efficiency of citicoline therapy on the level and variability of both systolic and ...
O. D. Ostroumova, N. Yu. Taranenko
doaj   +2 more sources

Citicoline Improves Human Vigilance and Visual Working Memory: The Role of Neuronal Activation and Oxidative Stress

open access: yesBasic and Clinical Neuroscience, 2020
Introduction: Psychomotor performance task is used to assess the arousal and cognitive functions of the central nervous system. Alternatively, human visual working memory reflects the capability of the individual’s short-term memory.
Hayder M. Al-kuraishy, Ali I. Al-Gareeb
doaj   +1 more source

Effects of Low-Dose Citicoline on the Electrical Conduction Function of the Crushed Sciatic Nerve of Rats

open access: yesDubai Medical Journal, 2023
Introduction: Citicoline has therapeutic and beneficial effects in a variety of neurologic disorders and neurodegenerative diseases. The aim of this study was to examine the beneficial effects of low doses of citicoline for the early period of ...
Serife Gökçe Çalışkan   +2 more
doaj   +1 more source

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