Results 31 to 40 of about 2,761 (203)

Supporting Info: Synthesis of Process related impurities of Citicoline and Citicoline sodium

open access: yes, 2023
NMR data for Citicoline ...
Nilesh Bonde (16430874)
core   +1 more source

Combined citicoline and docosahexaenoic acid treatment improves cognitive dysfunction following transient brain ischemia

open access: yesJournal of Pharmacological Sciences, 2019
Phospholipids are structural components of cellular membranes that play important roles as precursors for various signaling pathways in modulating neuronal membrane function and maintenance of the intracellular environment.
Eri Nakazaki   +7 more
doaj   +1 more source

Citicoline for the Management of Patients with Traumatic Brain Injury in the Acute Phase: A Systematic Review and Meta-Analysis

open access: yesLife, 2023
Background: Citicoline or CDP-choline is a neuroprotective/neurorestorative drug used in several countries for the treatment of traumatic brain injury (TBI).
Julio José Secades   +3 more
doaj   +1 more source

Citicoline Modifies the Expression of Specific miRNAs Related to Cardioprotection in Patients with ST-Segment Elevation Myocardial Infarction Subjected to Coronary Angioplasty

open access: yesPharmaceuticals, 2022
Extracellular vesicles are recognized as signaling mediators between cells both in physiological and pathological communication. In this work, we explored the potential effect of citicoline to modify relevant proteins or miRNAs for cardioprotection in ...
Alejandro Silva-Palacios   +11 more
doaj   +1 more source

Citicoline: A Candidate for Adjunct Treatment of Multiple Sclerosis [PDF]

open access: yesPharmaceuticals, 2021
In remitting–relapsing multiple sclerosis (RR-MS), relapses are driven by autoreactive immune cells that enter the brain and spinal cord and damage myelin sheaths of axons in white and grey matter, whereas during remissions myelin is repaired by activated oligodendroglial cells.
Paweł Grieb   +5 more
openaire   +4 more sources

Citicoline in hypoxic ischemic encephalopathy in neonates: a randomized controlled trial

open access: yesItalian Journal of Pediatrics, 2023
Background Hypoxic-ischemic encephalopathy (HIE) is one of the major complications that can lead to death or disability in neonates. We assessed the effect of citicoline as a neuroprotector in neonates with moderate and severe HIE.
Abeer Salamah   +3 more
doaj   +1 more source

Citicoline in Ophthalmological Neurodegenerative Disease: A Comprehensive Review [PDF]

open access: yesPharmaceuticals, 2021
Cytidine 5’-diphosphocholine has been widely studied in systemic neurodegenerative diseases, like Alzheimer’s disease, Parkinson’s disease, and brain ischemia. The rationale for the use of citicoline in ophthalmological neurodegenerative diseases, including glaucoma, anterior ischemic optic neuropathy, and diabetic retinopathy, is founded on its ...
Francesco Oddone   +10 more
openaire   +4 more sources

Safety of L-alpha-glycerylphosphorylcholine (L-alpha-GPC) from soya phospholipids (lecithin) as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

open access: yesEFSA J
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on L‐alpha‐glycerylphosphorylcholine (L‐alpha‐GPC) as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel on Nutrition   +27 more
europepmc   +2 more sources

Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage

open access: yesFrontiers in Cell and Developmental Biology, 2020
Aminoglycoside-induced hair cell (HC) loss is one of the most important causes of hearing loss. After entering the inner ear, aminoglycosides induce the production of high levels of reactive oxygen species (ROS) that subsequently activate apoptosis in ...
Zhenhua Zhong   +18 more
doaj   +1 more source

Citicoline May Prevent Cognitive Decline in Patients with Cerebrovascular Disease

open access: yes, 2023
Marta Almeria,1,2 Ignacio Alvarez,2 Jessica Molina-Seguin,1 Sarah Besora,1 Mariateresa Buongiorno,1,2 Silvia Romero,1 Laura Casas,1 Cristina Cano,2 Judith Castejon,2 Sonia Arribas,2 Jerzy Krupinski1,3 1Departament de Neurologia, Fundació Assistencial ...
Alvarez I   +10 more
core  

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