Results 41 to 50 of about 4,987 (254)
Citicoline on the Barthel Index
Indian Journal of Pharmacology, 2023 INTRODUCTION: Traumatic brain injury (TBI) is a paramount factor in mortality and morbidity. The clinical trials conducted to investigate the efficacy of neuroprotective agents, such as citicoline, as a therapeutic alternative for TBI have presented divergent findings.
Mahmoodkhani, Mehdi +4 more
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Citicoline in hypoxic ischemic encephalopathy in neonates: a randomized controlled trial
Italian Journal of Pediatrics, 2023 Background Hypoxic-ischemic encephalopathy (HIE) is one of the major complications that can lead to death or disability in neonates. We assessed the effect of citicoline as a neuroprotector in neonates with moderate and severe HIE.
Abeer Salamah +3 more
doaj +1 more source
Liposomal Encapsulation of Citicoline for Ocular Drug Delivery
International Journal of Molecular Sciences, 2023 Glaucoma represents a group of neurodegenerative diseases characterized by optic nerve damage and the slowly progressive death of retinal ganglion cells. Glaucoma is considered the second leading cause of irreversible blindness worldwide. Pharmaceutical treatment of glaucoma is critical because of the properties of the ocular barrier that limit the ...
Bonechi, Claudia +8 more
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Assessment of visual contrast function and effects of citicoline treatment in children with visual impairment [PDF]
, 2014 Purpose: The present studies address the questions if visual dysfunction in severely visually impaired children can be measured with contrast tests high or low, how it relates to their visual abilities assessed with behavioural methods and if visual ...
Siddiqui, Aamir
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Citicoline in addictive disorders: a review of the literature [PDF]
The American Journal of Drug and Alcohol Abuse, 2014 Citicoline is a dietary supplement that has been used as a neuroprotective agent for neurological disorders such as stroke and dementia. Citicoline influences acetylcholine, dopamine, and glutamate neurotransmitter systems; serves as an intermediate in phospholipid metabolism; and enhances the integrity of neuronal membranes.
Nicholas D, Wignall, E Sherwood, Brown
openaire +2 more sources
Concurrent analysis of Simvastatin and citicoline using a Reversed-phase High Performance Liquid Chromatography-Ultra Violet Method [PDF]
Trends in Pharmaceutical Sciences, 2019 To develop and evaluate a sensitive, accurate, rapid and reproducible high performance liquid chromatography analytical method for concurrent assay of simvastatin, a hyperlipidemia controlling agent, and citicoline, a psychostimulant agent, a C18 column (
Negin Mozafari +4 more
doaj +1 more source
Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage
Frontiers in Cell and Developmental Biology, 2020 Aminoglycoside-induced hair cell (HC) loss is one of the most important causes of hearing loss. After entering the inner ear, aminoglycosides induce the production of high levels of reactive oxygen species (ROS) that subsequently activate apoptosis in ...
Zhenhua Zhong +18 more
doaj +1 more source
Mild cognitive impairment treatment issues
Неврология, нейропсихиатрия, психосоматика, 2022 The development of dementia is preceded by mild cognitive impairment (MCI), the treatment of which can slow down the transformation of MCI into dementia. The article discusses drug and non-drug therapies for MCI.
L. A. Shсhepankevich +6 more
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Citicoline Ameliorates Neuro- and Genotoxicity Induced by Acute Malathion Intoxication in Rats [PDF]
Journal of Bioscience and Applied Research, 2019 Objective: In the present study, we explored the therapeutic potential of citicoline in preventing malathion induced neurotoxicity and genotoxicity. Citicoline has been shown to act as a neuroprotective in experimental animal models of ischemia and other
Asmaa Galal +4 more
doaj +1 more source
A Statistical Model for Stroke Outcome Prediction and Treatment Planning
, 2016 Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit +3 more
core +1 more source