Results 61 to 70 of about 4,987 (254)
Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study
NMR in Biomedicine, Volume 39, Issue 4, April 2026.Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano +5 more
wiley +1 more source
Use of a 3-item short-form version of the Barthel Index for use in stroke: systematic review and external validation [PDF]
, 2017 Background and Purpose—There may be a potential to reduce the number of items assessed in the Barthel Index (BI), and shortened versions of the BI have been described.
Ali, Myzoon +5 more
core +2 more sources
Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era
Advanced Science, Volume 13, Issue 18, 27 March 2026.This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley +1 more source
PERAN CITICOLINE DALAM MENCEGAH NYERI NEUROPATIK PASCACEDERA SARAF SCIATICUS PADA TIKUS PUTIH (RATTUS NORVEGICUS) [PDF]
, 2012 Citicoline (CDP-choline) merupakan senyawa endogen yang berfungsi sebagai senyawa intermediate dalam sintesis fosfolipid membran, sintesis asetilkolin dan sebagai donor metal. Citicoline dapat memberikan efek kolinergik dan neuroprotektif.
Yessi Handini
core
CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.Optic neuropathy and glaucoma cause permanent visual deficits via retinal ganglion cell (RGC) loss and axon degeneration, affecting millions worldwide. Current treatments slow disease progression but cannot restore lost vision due to regeneration failure in adult RGCs.
Emma Beard +4 more
wiley +1 more source
Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]
, 2019 Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core
Disorders of the immune status in patients with chronic cerebral ischemia; differentiated pharmacological correction [PDF]
, 2018 The objective of the study is to establish the immune disorder patterns in patients with CCI I-II associated with arterial hypertension and to develop differentiated pharmacological methods for their ...
Bystrova, N. A. +2 more
core +2 more sources
Back Again to the Future: A New Era for Cerebroprotection
Annals of Neurology, Volume 99, Issue 1, Page 19-34, January 2026.Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley +1 more source
Jurnal Kesehatan Andalas, 2014 AbstrakTujuan penelitian ini adalah untuk menilai pengaruh lamanya pemberian citicoline dalam memperbaiki kualitas RNFL dan lapang pandangan pada POAG. Penelitian ini dilakukan pada pasien POAG yang datang dari bulan September 2010 – Januari 2011 dengan ...
Kemala Sayuti, Harmen ., Hondrizal .
doaj
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Chung‐Jansen Syndrome (CJS) is a rare autosomal dominant neurodevelopmental disorder caused by heterozygous mutations in the PHIP gene (6q14.1). It is characterized by developmental delay, intellectual disability, behavioral disturbances including autism spectrum disorder and attention deficit hyperactivity disorder, obesity, and distinct ...
Maedeh Khalili +3 more
wiley +1 more source