Results 61 to 70 of about 313,761 (243)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Effect of Spherical Aberration on the Optical Quality after Implantation of Two Different Aspherical Intraocular Lenses

open access: yesJournal of Ophthalmology, 2017
Purpose. To compare the effect of spherical aberration on optical quality in eyes with two different aspherical intraocular lenses. Methods. 120 eyes of 60 patients underwent phacoemulsification.
Michael Lasta   +3 more
doaj   +1 more source

Comparison of higher order wavefront aberrations with four aberrometers

open access: yesIndian Journal of Ophthalmology, 2019
Purpose: To evaluate the agreement of selected higher order aberration measurements between aberrometers based on three different wavefront technologies.
William H Cook   +3 more
doaj   +1 more source

Evaluation of the optical performance for aspheric intraocular lenses in relation with tilt and decenter errors.

open access: yesPLoS ONE, 2020
PURPOSE:To evaluate and compare the effect of misalignment and tilt on the optical performance of different aspheric intraocular lens (IOL) designs. METHODS:Three aspheric IOLs with a different quantity of spherical aberration (SA) have been designed and
Jesús Pérez-Gracia   +4 more
doaj   +1 more source

Demo 22-21 Spherical Aberration

open access: yes, 2001
A lens that has a spherical shape will exhibit spherical aberration; the position at which parallel light rays focus is closer to the lens for rays further away from the optic axis. When a stop is placed over the outer part of the lens and the distance

core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Accommodation and spherical aberration

open access: yes, 1997
Purpose\ud \ud The accommodation response to changing levels of longitudinal spherical aberration (LSA) was measured. The LSA of the eye is known to change from positive to negative as the level of accommodation of the eye increases.
Goode, Andrew   +2 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Effect of Surface Error Distribution and Aberration on Electromagnetic Performance of a Reflector Antenna

open access: yesInternational Journal of Antennas and Propagation, 2019
In this paper, a method based on the Zernike distribution and the optical aberration is proposed to investigate the effects of the distribution characteristics of surface distortions of a reflector antenna on its electromagnetic performance (EMP).
Binbin Xiang, Congsi Wang, Peiyuan Lian
doaj   +1 more source

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