Results 51 to 60 of about 125,093 (294)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Steerable solid propellant rocket motor Patent [PDF]

open access: yes, 1964
Steerable solid propellant rocket motor adapted to effect payload orientation as multistage rocket stage or reduce velocity as ...
Raggio, C. W., Jr.
core   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset. [PDF]

open access: yesPLoS ONE, 2011
Mutations in superoxide dismutase (SOD1) are causative for inherited amyotrophic lateral sclerosis. A proportion of SOD1 mutant protein is misfolded onto the cytoplasmic face of mitochondria in one or more spinal cord cell types.
Christine Vande Velde   +9 more
doaj   +1 more source

Thermodynamics of DNA packaging inside a viral capsid: the role of DNA intrinsic thickness

open access: yes, 2003
We characterize the equilibrium thermodynamics of a thick polymer confined in a spherical region of space. This is used to gain insight into the DNA packaging process. The experimental reference system for the present study is the recent characterization
Arsuaga   +29 more
core   +1 more source

Compaction of Quasi One-Dimensional Elastoplastic Materials [PDF]

open access: yes, 2017
Insight in the crumpling or compaction of one-dimensional objects is of great importance for understanding biopolymer packaging and designing innovative technological devices.
Bonn, Daniel   +4 more
core   +3 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Drive Current Calculation and Analysis of Permanent Magnet Spherical Motor Based on Torque Analytical Model and Particle Swarm Optimization

open access: yesIEEE Access, 2020
In order to determine the currents required in different attitudes and torque target conditions, this paper proposes a calculation method for drive currents of permanent magnet spherical motors based on three-dimensional magnetic field, torque analytical
Rui Zhou   +4 more
doaj   +1 more source

Spacecraft attitude sensor [PDF]

open access: yes, 1973
A system for sensing the attitude of a spacecraft includes a pair of optical scanners having a relatively narrow field of view rotating about the spacecraft x-y plane.
Davidson, A. C., Grant, M. M.
core   +1 more source

Sticky physics of joy: On the dissolution of spherical candies

open access: yes, 2012
Assuming a constant mass-decrease per unit-surface and -time we provide a very simplistic model for the dissolution process of spherical candies. The aim is to investigate the quantitative behavior of the dissolution process throughout the act of eating ...
Andreas Windisch   +3 more
core   +1 more source

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