Results 71 to 80 of about 394,445 (282)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Branched Spherical CR structures on the complement of the figure eight knot

open access: yes, 2013
We obtain a branched spherical CR structure on the complement of the figure eight knot with a given holonomy representation (called rho_2). There are essentially two boundary unipotent representations from the complement of the figure eight knot into PU ...
Falbel, Elisha, Wang, Jieyan
core   +3 more sources

Spherical indecomposable representations of Lie superalgebras

open access: yesJournal of Algebra, 2020
We present a classification of all spherical indecomposable representations of classical and exceptional Lie superalgebras. We also include information about stabilizers, symmetric algebras, and Borels for which sphericity is achieved. In one such computation, the symmetric algebra of the standard module of $\mathfrak{osp}(m|2n)$ is computed, which in ...
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Representations of rational Cherednik algebras

open access: yes, 2005
This paper surveys the representation theory of rational Cherednik algebras. We also discuss the representations of the spherical subalgebras. We describe in particular the results on category O.
Rouquier, Raphael
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Coupling different levels of resolution in molecular simulations

open access: yes, 2009
Simulation schemes that allow to change molecular representation in a subvolume of the simulation box while preserving the equilibrium with the surrounding introduce conceptual problems of thermodynamic consistency.
Kremer, Kurt   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Cubic Spherical Neutrosophic Sets and Selection of Electric Truck Using Cosine Similarity Measure [PDF]

open access: yesNeutrosophic Sets and Systems
The concepts of cubic spherical neutrosophic sets (CSNSs), introduced and investigated by Gomathi et al. [5], offer a geometric representation of collection of neutrosophic sets (NSs), enhancing their ability to capture uncertainty.
S. Krishnaprakash   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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