Results 121 to 130 of about 20,351 (298)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Mini-Workshop: Spherical Varieties and Automorphic Representations

, 2013
This workshop brought together, for the first time, experts on spherical varieties and experts on automorphic forms, in order to discuss subjects of common interest between the two fields.

core   +2 more sources

LiDAR-Radar Dual-Stream Pointcloud Aggregation Mid-Fusion With Multi-Coordinate System for 3D Semantic Segmentation

IEEE Access
This paper proposes Dual-stream Point aggregation Mid-fusion with Multi-coordinate system (DPMM), which leverages LiDAR-radar fusion with velocity information and 3D coordinate compatibility for improved semantic segmentation in autonomous driving. While
Ayoung Lee, Sungpyo Sagong, Heeseong Lee, Kyongsu Yi   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Spherical and Symmetric Supervarieties [PDF]

, 2020
We develop and study the notion of a spherical supervariety, which is a generalization of the classical notion of a spherical variety in algebraic geometry.
Sherman, Alexander
core  

Numerical study on inter-particle effects for multiple reacting biomass and coal particles based on Micro-CT morphology

Heliyon
Co-firing of biomass with coal combines the environmental benefits of renewable biomass with the high energy content of coal. Although the common numerical simulation treats the biomass and coal particles with ideal morphology, real particles often ...
Dongyu Liang
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Spherical representations of reductive Lie super algebras

, 2011
The idea of describing the eigenvalues of bosonic and fermionic fields in quantum field theory by commuting and anticommuting variables led to the development of super manifolds in the 1970s.
Schmittner, Sebastian E.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Calogero-Sutherland-type quantum systems, generalized hypergeometric functions and superintegrability for integral chains

Journal of High Energy Physics
We reinvestigate the Calogero-Sutherland-type (CS-type) models and generalized hypergeometric functions. We construct the generalized CS operators for circular, Hermite, Laguerre, Jacobi and Bessel cases and establish the generalized Lassalle-Nekrasov ...
Fan Liu, Rui Wang, Jie Yang, Wei-Zhong Zhao   +3 more
doaj   +1 more source