Results 81 to 90 of about 166,550 (276)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Continuum corrections to the level density and its dependence on excitation energy, n-p asymmetry, and deformation [PDF]

, 2004
In the independent-particle model, the nuclear level density is determined from the neutron and proton single-particle level densities. The single-particle level density for the positive-energy continuum levels is important at high excitation energies ...
A. Bohr, A. Böhm, A. V. Ignatyuk, A. V. Ignatyuk, D. Hilscher, D. R. Dean, E. Beth, E. Erba, G. Gamov, J. Binney, K.-H. Schmidt, L. G. Sobotka, M. Santo, P. J. Siemens, R. G. Newton, R. J. Charity, R. W. Hasse, S. Chandrasekhar, V. M. Strutinsky, W. D. Myers   +19 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Prediction of lateral surface, volume and sphericity of pomegranate using MLP artificial neural network [PDF]

Journal of Agricultural Machinery, 2015
Introduction: Fast and accurate determination of geometrical properties of agricultural products has many applications in agricultural operations like planting, cultivating, harvesting and post-harvesting.
A Rohani, S. I Saedi, H Gerailue, M. H Aghkhani   +3 more
doaj   +1 more source

The effect of many sources on the genuine multiparticle correlations [PDF]

, 2000
We report on a study aimed to explore the dependence of the genuine multiparticle correlations on the number of sources when the influence of other possible factors during multihadron production are avoided. The analysis utilised the normalised cumulants
Abbiendi, Adamovich, Adamovich, Agababyan, Alexander, Allison, Biyajima, Buschbeck, Bøggild, Carruthers, Carruthers, Chekanov, De Wolf, Edward K.G. Sarkisyan, Gideon Alexander, Jain, Jain, Lipa, Sjöstrand, Suzuki   +19 more
core   +2 more sources

Spherical roots of spherical varieties [PDF]

Annales de l'Institut Fourier, 2014
Brion proved that the valuation cone of a complex spherical variety is a fundamental domain for a finite reflection group, called the little Weyl group. The principal goal of this paper is to generalize this theorem to fields of characteristic unequal to 2. We also prove a weaker version which holds in characteristic 2, as well.
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Accurate Detection and Analysis of Pore Defects in Laser Powder Bed Fusion WE43 Magnesium Alloys

Micromachines
To explore the size, morphology, and distribution patterns of internal pore defects in WE43 magnesium alloy formed by laser powder bed fusion (LPBF), as well as their impact on its mechanical properties, computer tomography (CT), metallographic ...
Zhengxing Men, Liang Wang, Xi Gao, Wen Chen, Chen Ji, Ziche Li, Kun Li   +6 more
doaj   +1 more source