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Hereditary spherocytosis

open access: yesLancet, The, 2008
Hereditary spherocytosis is a common inherited disorder that is characterised by anaemia, jaundice, and splenomegaly. It is reported worldwide and is the most common inherited anaemia in individuals of northern European ancestry. Clinical severity is variable with most patients having a well-compensated haemolytic anaemia.
Silverio Perrotta   +2 more
exaly   +5 more sources

Hereditary Spherocytosis

Clinics in Haematology, 1975
Studies of the clinical features of hereditary spherocytosis since 1871 and laboratory investigation of the cellular abnormalities since 1940 have led to the characterization of hereditary spherocytosis as a prime example of a Mendelian dominant, genetically determined disorder of the erythrocyte membrane.
A J, Bellingham, T A, Prankerd
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Hereditary Spherocytosis

JAMA: The Journal of the American Medical Association, 1989
Hereditary spherocytosis is the most common inherited anemia in persons of northern European descent. In 75 percent of cases, the condition is inherited in an autosomal dominant fashion. Patients usually present with splenomegaly, jaundice and anemia.
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Hereditary spherocytosis in infancy

The Journal of Pediatrics, 1957
Summary A case of hereditary spherocytosis posed a difficult diagnostic problem during the first months of life. Spherocytosis was not observed during the neonatal period. The classification of the hemolytic anemia was partially obscured by the presence of a large proportion of donor blood.
Geoffrey C. Robinson, J.M. McKenty
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Hereditary Spherocytosis in the Negro

Archives of Pediatrics & Adolescent Medicine, 1957
Congenital spherocytosis is a disease characterized by a varying degree of anemia, microspherocytes in the peripheral blood smear, splenomegaly, and increased hemolysis in hypotonic saline solutions. Although probably recognized1and treated2in the latter part of the 19th century, it was first accurately described as a clinical entity by Minkowski3in ...
A H, KLINE, G H, HOLMAN
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Spectrin and Spherocytosis

New England Journal of Medicine, 1982
Knowledge of the structure and function of the red-cell membrane has increased during the past several years.
openaire   +2 more sources

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