Results 91 to 100 of about 315,745 (316)

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang   +7 more
wiley   +1 more source

Gamma-Rays from Positron Annihilation

open access: yes, 2009
SPI on INTEGRAL has provided spectra and a map of the sky in the emission from annihilations of positrons in the interstellar medium of our Galaxy.
Diehl, Roland, Leising, Mark
core   +1 more source

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

open access: yesAdvanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui   +8 more
wiley   +1 more source

Assesmen Kelangkaan Air di DAS Semajid Kabupaten Pamekasan

open access: yesJurnal Teknika
Penelitian ini bertujuan melakukan asesmen kelangkaan air menggunakan indek kelangkaan air Water Scarcity Indek (WSI) dan kelangkaan air irigasi faktor K.
Agil Priyanto   +2 more
doaj   +1 more source

Aldilà del trauma: il pensiero ristretto e l’eroe capovolto

open access: yesRicerca Psicoanalitica, 2020
In questo contributo viene analizzata la mentalità corrente alla luce del paradigma violenza-vittimismo che la caratterizza. Viene accostata la scena sadomasochista come scena prototipo di tale paradigma per cogliere gli elementi che potrebbero ...
Laura Ambrosiano
doaj   +1 more source

Astrocytic TIA1‐Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model

open access: yesAdvanced Science, EarlyView.
Astrocytic TIA1‐mediated stress granules (SGs) promote demyelination by sequestering the mRNA of cholesterol synthesis genes. In this model, astrocytic TIA1‐mediated SGs were increased in the optic nerves of EAE mice, leading to the downregulation of cholesterol synthesis genes such as HMGCS1 through sequestration of their mRNA into SGs, which ...
Zheyu Fang   +11 more
wiley   +1 more source

Integrated Ultrasound Device for Precision Bladder Volume Monitoring via Acoustic Focusing and Machine Learning

open access: yesAdvanced Science, EarlyView.
We present a conformable wearable ultrasound patch for noninvasive bladder volume monitoring. A flexible PZT array combined with a concave acoustic lens concentrates acoustic energy and improves depth selectivity through the anterior pelvic wall.
Long Long Cao   +4 more
wiley   +1 more source

SPI Measurements of Galactic 26Al

open access: yes, 2003
The precision measurement of the 1809 keV gamma-ray line from Galactic $^{26}$Al is one of the goals of the SPI spectrometer on INTEGRAL with its Ge detector camera. We aim for determination of the detailed shape of this gamma-ray line, and its variation
A. von Kienlin   +32 more
core   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

open access: yesAdvanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong   +21 more
wiley   +1 more source

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