Results 71 to 80 of about 310,415 (286)
HeliyonConsidering the need to gain a deeper understanding of the protective factors associated with coping with food insecurity, specifically in times of severe prolonged stress, the current longitudinal study seeks to examine the role of optimism in the ...
Shani Pitcho +4 more
doaj +1 more source
An evaluation of the RAPID assessment-based process improvement method for small firms [PDF]
, 2005 [Abstract]: With increasing interest by the software development community in software process improvement (SPI), it is vital that SPI programs are evaluated and the reports of lessons learned disseminated.
Cater-Steel, Aileen +2 more
core
Gamma-Ray Burst Detection with INTEGRAL/SPI [PDF]
, 2003 The spectrometer SPI, one of the two main instruments of the INTEGRAL spacecraft, has strong capabilities in the Field of Gamma-Ray Burst (GRB) detections. In its 16 degree Field of view (FoV) SPI is able to trigger and to localize GRBs.
Arend, Nikolas +4 more
core +4 more sources
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, EarlyView.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
, 2011 Significant advances have been made in the understanding of the diffuse Galactic hard X-ray continuum emission using data from the INTEGRAL observatory. The diffuse hard power-law component seen with the INTEGRAL/SPI spectrometer has been identified with
Andrew W. Strong +27 more
core +1 more source
Advanced Science, EarlyView.4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang +7 more
wiley +1 more source
Discrete Mathematics, 2012 Let $G = (V,E)$ be a graph and let $r,s,k$ be positive integers. "Revolutionaries and Spies", denoted $\cG(G,r,s,k)$, is the following two-player game. The sets of positions for player 1 and player 2 are $V^r$ and $V^s$ respectively. Each coordinate in $p \in V^r$ gives the location of a "revolutionary" in $G$.
Howard, David, Smyth, Clifford
openaire +3 more sources
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
Relationship between NAFLD and coronary artery disease: A Mendelian randomization study
Hepatology, EarlyView., 2022 Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren +4 more
wiley +1 more source
Advanced Science, EarlyView.Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia +4 more
wiley +1 more source