Results 61 to 70 of about 64,504 (308)

A Monoclonal Antibody with a High Affinity for Ricin Isoforms D and E Provides Strong Protection against Ricin Poisoning

open access: yesToxins
Ricin is a highly potent toxin that has been used in various attempts at bioterrorism worldwide. Although a vaccine for preventing ricin poisoning (RiVax™) is in clinical development, there are currently no commercially available prophylaxis or ...
Loïs Lequesne   +11 more
doaj   +1 more source

Análisis comparativo de índices de sequía en Andalucía para el periodo 1901-2012

open access: yesCuadernos de Investigación Geográfica, 2016
El estudio del comportamiento temporal de la sequía a partir de series meteorológicas constituye una importante herramienta de actuación y prevención ante este fenómeno natural de carácter extremo, que ocasiona importantes impactos económicos, sociales y
M. Peña-Gallardo   +3 more
doaj   +1 more source

Assessment the effect of drought and land use change on vegetation using Landsat data [PDF]

open access: yesDesert, 2019
Drought is a disaster phenomenon especially in arid and semi-arid areas. Vegetation and its production play a main role in the social and economic issues in every country.
S. Ahmadi   +4 more
doaj   +1 more source

The Revolution of Lateral Flow Assay in the Field of AMR Detection

open access: yesDiagnostics, 2022
The global spread of antimicrobial resistant (AMR) bacteria represents a considerable public health concern, yet their detection and identification of their resistance mechanisms remain challenging.
Hervé Boutal   +5 more
doaj   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

open access: yesAdvanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao   +7 more
wiley   +1 more source

Investigation of Climate Change Effect on Drought Characteristics in the Future Period using the HadCM3 model (Case Study: Khoy Station, Northwest of Iran) [PDF]

open access: yesDesert, 2017
Investigation of drought event has a great importance in the natural resources and water resources management and planning. In this research, the effect of the climate change on drought characteristics in Khoy station was investigated using the HadCM3 ...
َA. Salehpour Jam   +4 more
doaj   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu   +18 more
wiley   +1 more source

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

open access: yesAngewandte Chemie, EarlyView.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson   +5 more
wiley   +2 more sources

Towards Reducing Food Wastage: Analysis of Degradation Products Formed during Meat Spoilage under Different Conditions

open access: yesFoods
Foodstuffs, particularly perishable ones such as meat, are frequently discarded once the best-before date has been reached, despite the possibility of their continued suitability for human consumption.
Elisa Uhlig   +4 more
doaj   +1 more source

Drought Forecasting in East Azarbayjan during time period of 2013-2022 [PDF]

open access: yesجغرافیا و توسعه, 2015
Based on the possible  increasing trend in global drought due to the climate change, analyzing this event in every region seems essential. In this study, downscaled temperature and precipitation data were obtained from 16 AOGCM models under A1B, A2 and ...
Seyedeh shima Poor ali hossein   +1 more
doaj   +1 more source

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