Results 121 to 130 of about 310,534 (357)

Realgar‐Induced CNS Toxicity: Exploring OTC‐Mediated Ornithine Regulation of ZBTB7A Inhibits Astrocyte Glycolysis Based on the Liver–Brain Axis

open access: yesAdvanced Science, EarlyView.
Arsenic in realgar induces CNS toxicity through direct and indirect effects: it activates ZBTB7A in astrocytes, which in turn inhibits glycolysis and impairs mice's learning, memory, and exploration; it also suppresses OTC in the liver to block the ornithine cycle, leading to blood ornithine accumulation that crosses into the frontal lobe and further ...
Ping Ye   +7 more
wiley   +1 more source

Burning a Graph is Hard [PDF]

open access: yes, 2015
Graph burning is a model for the spread of social contagion. The burning number is a graph parameter associated with graph burning that measures the speed of the spread of contagion in a graph; the lower the burning number, the faster the contagion ...
Bonato, Anthony   +2 more
core  

Multiscale Construction, Evaluation, and Application of Organoids

open access: yesAdvanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma   +5 more
wiley   +1 more source

Integrin‐Piezo1 Axis Drives ECM Remodeling and Invasion of 3D Breast Epithelium

open access: yesAdvanced Science, EarlyView.
Mechanical stiffening of the extracellular matrix around mature mammary acini induces sequential remodeling phases. An early response disrupts the basement membrane and promotes fibronectin secretion, followed by delayed invasion with matrix reorganization and proliferation.
Kabilan Sakthivel   +8 more
wiley   +1 more source

The Woodlouse Hunter Occurs in Michigan (Araneae: Dysderidae: \u3ci\u3eDysdera Crocata\u3c/i\u3e C.l. Koch 1838) [PDF]

open access: yes, 2016
We document the occurrence of the spider, Dysdera crocata C.L. Koch, in Michigan. Specimens have been collected from Bay, Branch, Ingham, Kent, Livingston, Macomb, Montcalm, Muskegon, Oakland, Washtenaw and Wayne Counties between 1975 ...
Cognato, Anthony I, O\u27Brien, Mark F
core   +2 more sources

Spatially Resolved Mapping of Voltage‐Gated Proton Channel Activity Reveals Delayed Proton Transport in Local Microenvironments

open access: yesAdvanced Science, EarlyView.
A revolutionary imaging platform integrating quantitative single‐molecule photobleaching with ratiometric fluorescence probes enables high‐throughput (≈2300 individually resolvable channels) mapping of individual proton channels in a large field (≈3000 µm2), overcoming the spatial and temporal limitations of conventional electrophysiology.
Jiahua Zhuang   +5 more
wiley   +1 more source

Identification of orb-web spider species and their food source through environmental DNA analysis

open access: yesJournal of Ecology and Environment
Spiders play a vital role in agricultural ecosystems by capturing and preying on small insects, thereby controlling the pests around crops. However, without directly collecting the specimen, it is challenging to accurately determine the species of the ...
Keonhee Kim, Seung Tae Kim
doaj   +1 more source

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