Results 181 to 190 of about 293,470 (339)

3D Culture in Functionalized FN‐Silk Networks Facilitate Proliferation, Differentiation and Phenotypic Stability of Mature Human Primary Cells and Stem Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
The authors present a new technique for 3D culture of mammalian cells with the support of a microfiber‐based network of fibronectin (FN)‐functionalized recombinant silk. This feasible 2‐step method results in highly viable free‐floating 3D cultures with tissue‐mimicking morphology.
Astrid Källén   +4 more
wiley   +1 more source

Lipopeptides as anti-infectives: a practical perspective

open access: yesOpen Life Sciences, 2009
Pirri Giovanna   +4 more
doaj   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

open access: yesCancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae   +16 more
wiley   +1 more source

Editorial: Frontiers in Silk Science and Technology

open access: yesFrontiers in Materials, 2021
Nicola Maria Pugno   +4 more
doaj   +1 more source

Mammalian Tolerance to Amino Acid Heterochirality

open access: yesChemBioChem, EarlyView.
Organisms preferentially use l‐amino acids (l‐AAs). However, de novo synthesized l‐AAs are in part converted to d‐AAs. The ribosome has a robust system to use l‐AAs for protein synthesis, whereas non‐ribosomal synthesis can also use d‐AAs. Furthermore, some AA residues can be post‐translationally isomerized through enzymatic or spontaneous processes ...
Sakiko Taniguchi   +4 more
wiley   +1 more source

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