Results 221 to 230 of about 387,621 (269)

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

Long-term immune response to mRNA anti-SARS-CoV-2 vaccination in patients with cancer. [PDF]

open access: yesFront Immunol
Lobo-Martins S   +24 more
europepmc   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

Genetic analysis of wheat ear architecture in F2 hybrid of tetraploid wheats Triticum aethiopicum and T. carthlicum and its computer phenotyping. [PDF]

open access: yesVavilovskii Zhurnal Genet Selektsii
Kruchinina YV   +5 more
europepmc   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Optimal Transport Theory to Extract Spiking Motifs

open access: yes
Grimaldi A   +5 more
europepmc   +1 more source

Antiretroviral therapy interferes with pseudovirus neutralization assays while Gag-specific T-cells influence mRNA vaccine outcomes in HIV patients. [PDF]

open access: yesSci Rep
Litwin SM   +22 more
europepmc   +1 more source

Comprehensive whole-genome characterization of SARS-CoV-2 strains in Jining China 2024-2025. [PDF]

open access: yesFront Microbiol
Yang H   +13 more
europepmc   +1 more source

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