Results 171 to 180 of about 76,288 (243)

Preferential renal tubular injury and increased renal sympathetic activity occur during the early stages of DOCA‐salt hypertension in male rats

Physiological Reports, Volume 14, Issue 11, June 2026.
Evaluation of cardiovascular parameters and renal mediators during the development of arterial hypertension in male DOCA‐Salt rats. Abstract Although renal dysfunction is present in arterial hypertension, the mechanisms underlying renal glomerular and tubular alterations remain incompletely understood.
Edina Da Luz Abreu, Rafael S. Carvalhal, Ana Caroline Marreiros, Stephanie F. Gerolin, Laura Barroso F. Oliveira, Maria Eduarda Abreu‐Cunha, Diogo B. Peruchetti, Cristiane D. Gil, Cássia T. Bergamaschi, Ruy R. Campos   +9 more
wiley   +1 more source

Cytotoxic T Cells Targeting Spike Glycoprotein Are Associated with Hybrid Immunity to SARS-CoV-2. [PDF]

J Immunol, 2023
Phan JM, Layton ED, Yu KKQ, Aguilar MS, Golez I, Franko NM, Logue JK, Rodda LB, Howard CA, Pepper M, Gale M, Chu HY, Seshadri C.   +12 more
europepmc   +1 more source

Ligand‐Based Pharmacophore Modeling and Structure‐Based Virtual Screening for Identifying Potential Therapeutic Agents Targeting the SARS‐CoV‐2 Spike Protein‐ACE2 Receptor Interaction

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
A protocol guided by ligand‐based pharmacophore modeling and structure‐based virtual screening enabled the identification of 1H‐pyrazol‐5‐ol derivatives as novel inhibitors of the SARS‐CoV‐2 spike protein. The lead inhibitors, C‐3 and C‐4, could serve as templates for the design of potent antiviral agents targeting viral entry into host cells ...
Timoteo Delgado‐Maldonado, Gilberto Vargas‐Salas, Debasish Bandyopadhyay, Adriana Moreno‐Rodríguez, Eyra Ortiz‐Pérez, Gildardo Rivera   +5 more
wiley   +1 more source

Insertion in the N-Terminal Domain of the SARS-CoV-2 Spike Glycoprotein Affects Antibody Recognition and Phenotypic Properties. [PDF]

Viruses
Ermolaeva EA, Zyrina AN, Sirazova DI, Lunin AS, Motov AS, Chernavtseva AD, Gancharova OS, Kozlovskaya LI, Shishova AA, Siniugina AA, Ishmukhametov AA.   +10 more
europepmc   +1 more source

Insights from the molecular docking analysis of gambogic acid with the Chikungunya spike glycoprotein E2. [PDF]

Bioinformation, 2023
Qamar S, Syeda A, Amjad Beg M, Irfan Qureshi M.   +3 more
europepmc   +1 more source

Beyond the Spike Glycoprotein: Mutational Signatures in SARS-CoV-2 Structural Proteins. [PDF]

Infect Dis Rep
Tonon E, Cecchetto R, Lotti V, Lagni A, Diani E, Palmisano A, Mantoan M, Montesarchio L, Palladini F, Turri G, Gibellini D.   +10 more
europepmc   +1 more source

An Ad5-Based COVID-19 Vaccine Encoding SARS-CoV-2 Spike Glycoprotein Induces Measurable Antibody and Cytokine Responses in Mice. [PDF]

Biotechnol J
Erendor F, Uzer F, Sanlioglu S.
europepmc   +1 more source

Cryo-EM structure of locked spike glycoprotein from bat SARS-like coronavirus WIV1, molecular dynamics and biophysics across host range. [PDF]

Proc Natl Acad Sci U S A
Liu C, Zheng J, Wang Y, Beck F, Nagy I, Bohn S, Plitzko JM, Baumeister W, Zhang X, Sun L, Zinzula L.   +10 more
europepmc   +1 more source

Understanding Mutations in Human SARS-CoV-2 Spike Glycoprotein: A Systematic Review & Meta-Analysis. [PDF]

Viruses, 2023
Kumar R, Srivastava Y, Muthuramalingam P, Singh SK, Verma G, Tiwari S, Tandel N, Beura SK, Panigrahi AR, Maji S, Sharma P, Rai PK, Prajapati DK, Shin H, Tyagi RK.   +14 more
europepmc   +1 more source

Spectroscopic secondary structure fingerprint of β-variant of SARS-CoV-2 spike glycoprotein. [PDF]

Eur Biophys J
Mosetti R, Mancini T, Bertelà F, Macis S, Luchetti N, Minicozzi V, Lupi S, D'Arco A.   +7 more
europepmc   +1 more source