Results 211 to 220 of about 76,288 (243)

Fine structure of a partition in the spike glycoprotein encoded in the SARS-CoV-2 genome

, 2022
Morimoto S.
europepmc   +1 more source

In-silico evaluation of natural alkaloids against the main protease and spike glycoprotein as potential therapeutic agents for SARS-CoV-2. [PDF]

PLoS One
Shah M, Yamin R, Ahmad I, Wu G, Jahangir Z, Shamim A, Nawaz H, Nishan U, Ullah R, Ali EA, Sheheryar, Chen K.   +11 more
europepmc   +1 more source

Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection. [PDF]

Nat Commun
Ávila-Nieto C, Vergara-Alert J, Amengual-Rigo P, Ainsua-Enrich E, Brustolin M, Rodríguez de la Concepción ML, Pedreño-Lopez N, Rodon J, Urrea V, Pradenas E, Marfil S, Ballana E, Riveira-Muñoz E, Pérez M, Roca N, Tarrés-Freixas F, Cantero G, Pons-Grífols A, Rovirosa C, Aguilar-Gurrieri C, Ortiz R, Barajas A, Trinité B, Lepore R, Muñoz-Basagoiti J, Perez-Zsolt D, Izquierdo-Useros N, Valencia A, Blanco J, Guallar V, Clotet B, Segalés J, Carrillo J.   +32 more
europepmc   +1 more source

Functional dissection of the spike glycoprotein S1 subunit and identification of cellular cofactors for regulation of swine acute diarrhea syndrome coronavirus entry. [PDF]

J Virol
Yang Y-L, Wang B, Li W, Cai H-L, Qian Q-Y, Qin Y, Shi F-S, Bosch B-J, Huang Y-W.   +8 more
europepmc   +1 more source

Inclusion of deuterated glycopeptides provides increased sequence coverage in hydrogen/deuterium exchange mass spectrometry analysis of SARS-CoV-2 spike glycoprotein. [PDF]

Rapid Commun Mass Spectrom
Haynes CA, Keppel TR, Mekonnen B, Osman SH, Zhou Y, Woolfitt AR, Baudys J, Barr JR, Wang D.   +8 more
europepmc   +1 more source

Stabilization of the Metastable Pre-Fusion Conformation of the SARS-CoV-2 Spike Glycoprotein through N-Linked Glycosylation of the S2 Subunit. [PDF]

Viruses
Zan F, Zhou Y, Chen T, Chen Y, Mu Z, Qian Z, Ou X.   +6 more
europepmc   +1 more source

Molecularly imprinted polypyrrole based sensor for the detection of SARS-CoV-2 spike glycoprotein

Electrochimica Acta, 2022
International audienceThis study describes the application of a polypyrrole-based sensor for the determination of SARS-CoV-2-S spike glycoprotein. The SARS-CoV-2-S spike glycoprotein is a spike protein of the coronavirus SARS-CoV-2 that recently caused ...
Vilma Ratautaite, Raimonda Boguzaite, Ernestas Brazys   +2 more
exaly   +2 more sources

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein [PDF]

Cell, 2020
SUMMARY The recent emergence of a novel coronavirus associated with an ongoing outbreak of pneumonia (Covid-2019) resulted in infections of more than 72,000 people and claimed over 1,800 lives. Coronavirus spike (S) glycoprotein trimers promote entry into cells and are the main target of the humoral immune response ...
Alexandra C Walls, Young-Jun Park, M Alejandra Tortorici   +2 more
exaly   +6 more sources

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Structural Bioinformatics to Unveil Weaknesses of Coronavirus Spike Glycoprotein Stability

2021
Alternative strategies for developing antiviral drugs are needed, as vaccines could not be the final answer against the present SARS CoV-2 outbreak, due to the still existing ambiguities in the immunological response to the virus. Thus, SARS CoV-2 enzymes have been thoroughly investigated to develop their inhibitors as antiviral drugs. We have searched
Bongini P., Trezza A., Bianchini M., Spiga O., Niccolai N.   +4 more
openaire   +2 more sources