Results 141 to 150 of about 403,301 (348)

Produksi Antibodi Poliklonal Menggunakan Protein Rekombinan RBD-spike Untuk Deteksi SARS-CoV-2 [PDF]

, 2023
Iryani Endah Febrianti, Yayuk Fatmawati, Intan Ria Neliana, Widhi Dyah Sawitri, Erlia Narulita, Bambang Sugiharto   +5 more
openalex   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

The effect of beta-globin intron and WPRE on transient expression of SARS-CoV-2 spike and generation of pseudotyped lentiviruses

Acta Virologica
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an enveloped, single-stranded RNA virus, is causative of coronavirus disease 2019 (COVID-19).
Hyeop Jin, Ye Rae Cho, Yong Tae Jung
doaj   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Discovery of thiadiazole-based small-molecule inhibitors of SARS-CoV-2 spike-ACE2 interaction through integrated computational prediction and experimental validation

Scientific Reports
The SARS-CoV-2 spike protein enables viral entry by binding to the human ACE2 receptor, making it a critical target for antiviral intervention. In this study, five small molecules derived from 1,3,4-thiadiazole scaffolds were identified as potential ...
Zakkia Gul, Syed Ahsan Shahid, Obaid-ur-Rahman Abid, Muhammad Waqas, Shazia Rafique, Ahmed E. Al-Sabri, Asma Sardar, Afrah F. Alkhuriji, Nawal M. Al-Malahi, Muhammad Irfan, Amjad Ali   +10 more
doaj   +1 more source

Antibodies against Receptor Binding Domain of SARS-CoV-2 spike protein induced by BNT162b2 vaccine: results from a pragmatic, real-life study

, 2021
Marcello Mariani, Maura Acquila, Gino Tripodi, Raffaele Spiazzi, Elio Castagnola   +4 more
openalex   +1 more source

Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters [PDF]

, 2022
Xueqiao Liu, Hong-Su Park, Yumiko Matsuoka, Celia Santos, Lijuan Yang, Cindy Luongo, Ian N. Moore, Reed F. Johnson, Nicole L. Garza, Peng Zhang, Paolo Lusso, Sonja M. Best, Ursula J. Buchholz, Cyril Le Nouën   +13 more
openalex   +1 more source

Causes and Consequences of Coronavirus Spike Protein Variability

Viruses
Coronaviruses are a large family of enveloped RNA viruses found in numerous animal species. They are well known for their ability to cross species barriers and have been transmitted from bats or intermediate hosts to humans on several occasions. Four of the seven human coronaviruses (hCoVs) are responsible for approximately 20% of common colds (hCoV ...
Fabian Zech, Christoph Jung, Timo Jacob, Frank Kirchhoff   +3 more
openaire   +5 more sources

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

Screening of inhibitors against SARS-CoV-2 spike protein and their capability to block the viral entry mechanism: A viroinformatics study

, 2021
Abd‐ElAziem Farouk, Mohammad Hassan Baig, Mohd Imran Khan, Tae Hwan Park, Saqer S. Alotaibi, Jae-June Dong   +5 more
openalex   +1 more source