Results 311 to 320 of about 403,301 (348)

Rationally designed, ACE2 mimetic binder to the SARS Cov-2 associated Spike protein for COVID-19 therapeutics and beyond. [PDF]

Sci Rep
Peters MH, Pei XY.
europepmc   +1 more source

Structural constraints acting on the SARS-CoV-2 spike protein reveal limited space for viral adaptation

Herzig JC, Magwira ML, Lovell SC.
europepmc   +1 more source

Structural and functional insights into the evolution of SARS-CoV-2 KP.3.1.1 spike protein. [PDF]

Cell Rep
Feng Z, Huang J, Baboo S, Diedrich JK, Bangaru S, Paulson JC, Yates JR, Yuan M, Wilson IA, Ward AB.   +9 more
europepmc   +1 more source

Mutational Stability Profiling and Functional Analysis of Spike Protein In Indian Sars Cov-2 Delta Variants: An In Silico Analysis

Prisho Mariam Paul, Krupakar Parthasarathy, Sudhanarayani S. Rao, Vignesh Sounderrajan, Sakthivel Jayaraj, Swetha Sunkar   +5 more
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Expression and purification of receptor binding domain of the Spike protein of SARS-CoV-2 of Wuhan strain

Fábio Antonio Busoli [UNIFESP] Vaz
openalex   +1 more source

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Spike Protein Fragments Promote Alzheimer’s Amyloidogenesis

ACS Applied Materials & Interfaces, 2023
Alzheimer's disease (AD) is a major cause of dementia inducing memory loss, cognitive decline, and mortality among the aging population. While the amyloid aggregation of peptide Aβ has long been implicated in neurodegeneration in AD, primarily through the production of toxic polymorphic aggregates and reactive oxygen species, viral infection has a less
Sujian Cao, Zhiyuan Song, Jinyu Rong, Nicholas Andrikopoulos, Xiufang Liang, Yue Wang, Guotao Peng, Feng Ding, Pu Chun Ke   +8 more
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Biomimetic SARS-CoV-2 Spike Protein Nanoparticles

Biomacromolecules, 2023
COVID-19 is an infectious respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus contains a crucial coat protein that engages with target cells via a receptor binding domain (RBD) on its spike protein. To better study the RBD and its therapeutic opportunities, we genetically engineered a simple fusion
Alvin Phan, Hugo Avila, J. Andrew MacKay
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Thermal Spikes in Protein

Journal of Applied Physics, 1962
A formula is shown relating the temperature of an infinite medium through which a fission fragment passes with the distance from the axis defined by the fission-fragment track. This formula has cylindrical symmetry, and represents a temperature distribution that has a maximum at the track and falls off exponentially with the radius.
A. Norman, P. Spiegler
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Electronic Spiking Protein-Based COVID Sensors

ECS Meeting Abstracts, 2021
Viruses are ultimate nanotechnology objects with cleverly designed capsid proteins to bind with cell membranes and exquisite DNA/RNA machinery to invade cells and replicate themselves using cells' machinery. Here I will discuss an electronic virus sensor that uses aptamers designed to bind with the COVID-19 spiking proteins S1 and S2 to capture the ...
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SARS-CoV-2 strain-specific anti-spike IgG ELISA utilizing spike protein produced by silkworms

Human Antibodies, 2023
BACKGROUND: A cost-effective and eco-friendly method is needed for the assessment of humoral immunity against SARS-CoV-2 in large populations. OBJECTIVE: We investigated the performance of an ELISA that uses silkworm-produced proteins to quantify the strain-specific anti-Spike IgG (anti-S IgG) titer. METHODS: The OD values for the anti-His-tag antibody,
Takeyuki, Goto, Tomoki, Sasaki, Yong, Chong, Masahiro, Taniguchi, Jae Man, Lee, Akitsu, Masuda, Takeru, Ebihara, Kenichiro, Shiraishi, Naoki, Tani, Akiko, Yonekawa, Kei, Gondo, Hiroyuki, Kuwano, Nobuyuki, Shimono, Hideyuki, Ikematsu, Koichi, Akashi, Takahiro, Kusakabe   +15 more
openaire   +2 more sources