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Spike Protein Fragments Promote Alzheimer’s Amyloidogenesis
ACS Applied Materials & Interfaces, 2023Alzheimer's disease (AD) is a major cause of dementia inducing memory loss, cognitive decline, and mortality among the aging population. While the amyloid aggregation of peptide Aβ has long been implicated in neurodegeneration in AD, primarily through the production of toxic polymorphic aggregates and reactive oxygen species, viral infection has a less
Sujian Cao +8 more
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Journal of Applied Physics, 1962
A formula is shown relating the temperature of an infinite medium through which a fission fragment passes with the distance from the axis defined by the fission-fragment track. This formula has cylindrical symmetry, and represents a temperature distribution that has a maximum at the track and falls off exponentially with the radius.
A. Norman, P. Spiegler
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A formula is shown relating the temperature of an infinite medium through which a fission fragment passes with the distance from the axis defined by the fission-fragment track. This formula has cylindrical symmetry, and represents a temperature distribution that has a maximum at the track and falls off exponentially with the radius.
A. Norman, P. Spiegler
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Cytoplasmic tail of coronavirus spike protein has intracellular targeting signals
Intracellular trafficking and localization studies of spike protein from SARS and OC43 showed that SARS spike protein is localized in the ER or ERGIC compartment and OC43 spike protein is predominantly localized in the lysosome. Differential localization
Manmeet Singh, Jayasri Das Sarma
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Functional Domains in the Spike Protein of Transmissible Gastroenteritis Virus
1995The coronavirus spike protein S is assumed to mediate essential biological functions, including recognition of target cells. Earlier studies from our and other groups identified two regions of the TGEV S (220K) protein possibly implicated in such functions. The first of these corresponds to the 224 amino acid N-terminal region which is deleted in PRCV,
Laude, Hubert +5 more
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Construction of a Ball‐and‐Spike Protein Supramolecule
Angewandte Chemie International Edition, 2006Kenji Sugimoto +4 more
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Allosteric perspective on the mutability and druggability of the SARS-CoV-2 Spike protein
Structure, 2022Zhen Wah Tan +2 more
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Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients
Cell Reports, 2021Yang Li, Qing Lei, Hongyan Hou
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