Results 311 to 320 of about 7,152,333 (341)

Endothelial Cell Activation by SARS-CoV-2 Spike Protein and Its RBD: Central Player of the Immunothrobotic Response in COVID-19. [PDF]

Curr Issues Mol Biol
Cano-Mendez A, Garcia-Larragoiti N, Ambriz-Murillo Y, Velez-Chavez J, Vega-Agavo R, Vazquez-Marrufo G, Higareda-Mendoza AE, Ochoa-Zarzosa A, Viveros-Sandoval ME.   +8 more
europepmc   +1 more source

Preparation and Immunological Efficacy Evaluation of mRNA Vaccines Targeting the Spike Protein of Bovine Coronavirus. [PDF]

Vaccines (Basel)
Liu S, Gong Z, Wang P, Chen F, Fu X, Fan H, Li Y, Han X, Chen J, Zhang L, Xue L, Bai H, Liu S, Huang L, Du W, Lin A, Xia J.   +16 more
europepmc   +1 more source

RETRACTION: Silencing SARS-CoV Spike Protein Expression in Cultured Cells by RNA Interference. [PDF]

FEBS Lett
europepmc   +1 more source

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Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19.

Cell Host and Microbe
SARS-CoV-2 infection is associated with long-lasting neurological symptoms, although the underlying mechanisms remain unclear. Using optical clearing and imaging, we observed the accumulation of SARS-CoV-2 spike protein in the skull-meninges-brain axis ...
Zhouyi Rong, H. Mai, Gregor Ebert, Saketh Kapoor, Victor G. Puelles, Jan Czogalla, Senbin Hu, Jinpeng Su, Danilo Prtvar, Inderjeet Singh, Julia Schädler, C. Delbridge, Hanno Steinke, Hannah Frenzel, Katja Schmidt, C. Braun, G. Bruch, Viktoria C. Ruf, Mayar Ali, K. Sühs, Mojtaba Nemati, Franziska Hopfner, Selin Ulukaya, Denise Jeridi, Daniele Mistretta, Ö. S. Çalışkan, Jochen Wettengel, Fatma Cherif, Z. I. Kolabas, Muge Molbay, I. Horvath, Shan Zhao, Natalie Krahmer, A. Ö. Yildirim, S. Ussar, Jochen Herms, Tobias B. Huber, Sabina Tahirovic, S. Schwarzmaier, Nikolaus Plesnila, G. Höglinger, B. Ondruschka, Ingo Bechmann, Ulrike Protzer, Markus Elsner, H. Bhatia, Farida Hellal, Ali Ertürk   +47 more
semanticscholar   +3 more sources

Spike Protein Fragments Promote Alzheimer’s Amyloidogenesis

ACS Applied Materials & Interfaces, 2023
Alzheimer's disease (AD) is a major cause of dementia inducing memory loss, cognitive decline, and mortality among the aging population. While the amyloid aggregation of peptide Aβ has long been implicated in neurodegeneration in AD, primarily through the production of toxic polymorphic aggregates and reactive oxygen species, viral infection has a less
Sujian Cao, Zhiyuan Song, Jinyu Rong, Nicholas Andrikopoulos, Xiufang Liang, Yue Wang, Guotao Peng, Feng Ding, Pu Chun Ke   +8 more
openaire   +2 more sources

Biomimetic SARS-CoV-2 Spike Protein Nanoparticles

Biomacromolecules, 2023
COVID-19 is an infectious respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus contains a crucial coat protein that engages with target cells via a receptor binding domain (RBD) on its spike protein. To better study the RBD and its therapeutic opportunities, we genetically engineered a simple fusion
Alvin Phan, Hugo Avila, J. Andrew MacKay
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Thermal Spikes in Protein

Journal of Applied Physics, 1962
A formula is shown relating the temperature of an infinite medium through which a fission fragment passes with the distance from the axis defined by the fission-fragment track. This formula has cylindrical symmetry, and represents a temperature distribution that has a maximum at the track and falls off exponentially with the radius.
A. Norman, P. Spiegler
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Electronic Spiking Protein-Based COVID Sensors

ECS Meeting Abstracts, 2021
Viruses are ultimate nanotechnology objects with cleverly designed capsid proteins to bind with cell membranes and exquisite DNA/RNA machinery to invade cells and replicate themselves using cells' machinery. Here I will discuss an electronic virus sensor that uses aptamers designed to bind with the COVID-19 spiking proteins S1 and S2 to capture the ...
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SARS-CoV-2 strain-specific anti-spike IgG ELISA utilizing spike protein produced by silkworms

Human Antibodies, 2023
BACKGROUND: A cost-effective and eco-friendly method is needed for the assessment of humoral immunity against SARS-CoV-2 in large populations. OBJECTIVE: We investigated the performance of an ELISA that uses silkworm-produced proteins to quantify the strain-specific anti-Spike IgG (anti-S IgG) titer. METHODS: The OD values for the anti-His-tag antibody,
Takeyuki, Goto, Tomoki, Sasaki, Yong, Chong, Masahiro, Taniguchi, Jae Man, Lee, Akitsu, Masuda, Takeru, Ebihara, Kenichiro, Shiraishi, Naoki, Tani, Akiko, Yonekawa, Kei, Gondo, Hiroyuki, Kuwano, Nobuyuki, Shimono, Hideyuki, Ikematsu, Koichi, Akashi, Takahiro, Kusakabe   +15 more
openaire   +2 more sources