Results 191 to 200 of about 130,477 (208)

Evolution of Multivalent Aptamer Corona for High‐Throughput Multiplexed Detection of Multiple Cancers

Advanced Science, EarlyView.
A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang, Baichuan Jin, Xin Dai, Haozhe Huang, Qiqi Liu, Jianqing Zhu, Haixing Ju, Qixun Chen, Yongmei Song, Weihong Tan, Yuan Liu   +10 more
wiley   +1 more source

Replication-incompetent viral vaccine vectors ChAdOx1 and MVA as tools for evaluating T-cell responses to naturally processed antigens in vitro. [PDF]

Virus Res
Nazki S, Reiné J, Kailath R, Gilbert S, Douradinha B.   +4 more
europepmc   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

Effect of nitrogen fertilizer regulation on rice panicle morphology, yield and economic benefits under low-temperature stress. [PDF]

Front Plant Sci
Du X, Zhang Y, Hou T, Zhao Z, Li D, Kang M, Wen X, Tang F, Abliz B, Qi Y, Yuan Q, Yuan J, Wang F.   +12 more
europepmc   +1 more source

Development and characterization of a pentylenetetrazol-induced convulsive seizure model in non-anaesthetized sheep. [PDF]

Biol Methods Protoc
Pustovit RV, Lankadeva YR, Soh MS, Berkovic SF, Reid CA, May CN.   +5 more
europepmc   +1 more source

Molecular characteristics and regulatory effects of dwarfing Rht genes in Triticum aestivum L. [PDF]

BMC Plant Biol
Wang YR, Shi J, He YY, Tao YL, Ren LT, Shao QQ, Chen X, Wu ZF, Li JC, Zheng JC.   +9 more
europepmc   +1 more source

K5 polysaccharides inhibit SARS-CoV-2 infection by preventing spike-proteolytic priming. [PDF]

Npj Viruses
Milanesi M, Urbinati C, Zimmermann L, Oreste P, Zani A, Caruso A, Caccuri F, Laketa V, Chlanda P, Wade RC, Rusnati M, Paiardi G.   +11 more
europepmc   +1 more source

A binary self-amplifying expression platform enabling lipid nanoparticle-free vaccines and nanomedicines. [PDF]

Nat Commun
Jefferies WA, Choi KB, Ribeca P, Kari S, Young JA, Hui E, Qi SY, Garrovillas E, Fan J, Cho BMY, Housh P, Welch T, Saranchova I, Pfeifer CG.   +13 more
europepmc   +1 more source